Kaia Skjærven

Scientist (PhD)
Telephone: 41458362
Department: Behov og velferd

My special interest area is related to early embryonic development in fish and how development is affected by environmental conditions such as nutrition, temperature, or toxicants. The main focus is related to how the different environmental conditions change the potential for gene expression in embryos, i.e. epigenetic changes. I am currently working with salmon, cod and zebrafish.



Subject area
Selected publications
Projects
Scientific publications


The main theme of my work is related epigenetics. The field of epigenetics is evolving dramatically, precisely because it is the link between heredity and environment. Epigenetics describes how the environment affects which of the genes that are turned on and off like a light switch. Environmental regulation of the genome can be inherited from the mother and father to the next generation, but how this regulation is controlled in fish is not known. Together with colleagues we study the effect of fish feed and environmental influences on epigenetic regulation of the genome.


K. H. Skjærven , P. A. Olsvik, R. N. Finn, E. Holen, and K. Hamre. Ontogenetic expression of maternal and zygotic genes in Atlantic cod embryos under ambient and thermally stressed conditions. Comp Biochem Physiol A Mol Integr Physiol. 2011 Jun;159(2):196-205.

K. H. Skjærven , S. Penglase, P. A. Olsvik and K. Hamre. Redox regulation in Atlantic cod ( Gadus morhua ) embryos developing under normal and heat stressed conditions. Free Radic Biol Med 57 (2013)29-38

K. H. Skjærven , K. Hamre, R. N. Finn and P. A. Olsvik. Thermal stress alters expression of genes involved in one carbon and DNA methylation pathways in Atlantic cod embryos. Comp Biochem Physiol A Mol Integr Physiol. 2014 Mar;173C:17-27.

  • 2015


    Pål Asgeir Olsvik, Heidi Amlund, Øystein Sæle, Ståle Ellingsen, Kaja Helvik Skjærven

    Impact of dietary selenium on methylmercury toxicity in juvenile Atlantic cod: A transcriptional survey

    Chemosphere; Volum 120. S. 199-205
    • År: 2015
  • 2014


    Kaja Helvik Skjærven, Kristin Hamre, Samuel Penglase, Roderick Nigel Finn, Pål Asgeir Olsvik

    Thermal stress alters expression of genes involved in one carbon and DNA methylation pathways in Atlantic cod embryos

    Comparative Biochemistry and Physiology A; Volum 173. S. 17-27
    • År: 2014

    Pål Asgeir Olsvik, Timothy Williams, Hai-Shan Tung, Leda Mirbahai, Monica Sanden, Kaja Helvik Skjærven, Ståle Ellingsen

    Impacts of TCDD and MeHg on DNA methylation in zebrafish (Danio rerio) across two generations

    Comparative Biochemistry and Physiology - Part C: Toxicology & Pharmacology; Volum 165. S. 17-27
    • År: 2014

    Kristin Hamre, Samuel Penglase, Josef Daniel Rasinger, Kaja Helvik Skjærven, Pål Asgeir Olsvik

    Ontogeny of redox regulation in Atlantic cod (Gadus morhua) larvae

    Free Radical Biology & Medicine; Volum 73. S. 337-348
    • År: 2014
  • 2013


    Kaja Helvik Skjærven, Samuel Penglase, Pål Asgeir Olsvik, Kristin Hamre

    Redox regulation in Atlantic cod (Gadus morhua) embryos developing under normal and heat-stressed conditions

    Free Radical Biology & Medicine; Volum 57. S. 29-38
    • År: 2013
  • 2011


    Kaja Helvik Skjærven, Pål Asgeir Olsvik, Roderick Nigel Finn, Elisabeth Holen, Kristin Hamre

    Ontogenetic expression of maternal and zygotic genes in Atlantic cod embryos under ambient and thermally stressed conditions

    Comparative Biochemistry and Physiology A; Volum 159.(2) S. 196-205
    • År: 2011

    Linn Silje Wathne Oftedal, Kaja Helvik Skjærven, Rosie Theresa Coyne, Bente Edvardsen, Thomas Rohrlack, Olav Skulberg, Stein Ove Doskeland, Lars Herfindal

    The apoptosis-inducing activity towards leukemia and lymphoma cells in a cyanobacterial culture collection is not associated with mouse bioassay toxicity

    Journal of Industrial Microbiology & Biotechnology; Volum 38.(4) S. 489-501
    • År: 2011
  • 2010


    Elisabeth Holen, Anette Kausland, Kaja Helvik Skjærven

    Embryonic stem cells isolated from Atlantic cod (Gadus morhua) and the developmental expression of a stage-specific transcription factor ac-Pou2

    Fish Physiology & Biochemistry; Volum 36. S. 1029-1039
    • År: 2010
  • 2009


    Siv Kristin Prestegard, Linn Silje Wathne Oftedal, Rosie Theresa Coyne, Gyrid Nygård, Kaja Helvik Skjærven, Gjert Knutsen, Stein Ove Doskeland, Lars Herfindal

    Marine Benthic Diatoms Contain Compounds Able to Induce Leukemia Cell Death and Modulate Blood Platelet Activity

    Marine Drugs; Volum 7.(4) S. 605-623
    • År: 2009
  • 2008


    Rosário F. Martins, Miguel F. Ramos, Lars Herfindal, José A. Sousa, Kaja Helvik Skjærven, Vitor M. Vasconcelos

    Antimicrobial and cytotoxic assessment of marine cyanobacteria - Synechocystis and synechococcus

    Marine Drugs; Volum 6.(1) S. 1-11
    • År: 2008
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