Curriculum Vitae

Personal information
Name: Abdullah Sami Madhun
Address: Havforskningsinstituttet  / Institute of Marine Research
P.Box 1870 Nordnes
NO-5817 Bergen,
Norway
Telephone(s) +47 55 23 63 60
Mobile: +47 947 85 883
E-mail: abdullah.madhun@imr.no

Work experience
-Head of Research Group (2010-): Health group, Institute of Marine Research, Bergen, Norway
-Senior Researcher (2003-2009): Influenza Centre, Medicine Faculty, University of Bergen, Norway.
-Senior Scientific officer (1999-2002): Vaccine section, Pharmaceutical Department, Norwegian Medicines Agency, Oslo, Norway.
-Teaching/research assistant (1993-1994): Biology and Biochemistry Department, BirZeit University, Palestine.
 

Education and training
-Dr. Scient. Virology/Immunology (1997-1998): Department of Molecular Biology, University of Bergen, Norway.
-M. Phil. Health Sciences (1994-1996): Department of Molecular Biology/Centre for International Health, University of Bergen, Norway
-Teaching Certificate (1991-1993): Department of Education, BirZeit University, West Bank, Palestine.
-B.Sc. Biology (1985-1992): Biology and Biochemistry Department, BirZeit University, West Bank, Palestine.
 

Scientific Grants
-Flupan (EU; FP5) “Preparing for an Influenza Pandemic” (2003-2007). Partners from the France, Italy, UK and Norway.
-Panfluvac (EU; FP6) "Efficacious vaccine formulation system for prophylactic control of influenza pandemics” (2007-11). Partners from the Netherlands, Germany, Italy, UK, Switzerland and Norway.
-Naspanvac” (EU; FP7) “Nasal pandemic influenza vaccine” (2008-11). Partners from UK, Ireland, France and Norway.
-Globvac (NFR, project leader) “The immunogenicity and protective efficacy of plant-derived influenza H5N1 vaccine in preclinical models”, (2008-11). Partners in from Germany, UK, USA and Norway.
 

Scientific Publications
-Madhun AS, Nøstbakken JK, Cox RJ. Intranasal cdi-GMP -adjuvanted plant-derived H5N1 vaccine induces high frequencies of multifunctional Th1 CD4+ cells and strong local and systemic antibody responses in mice. Manuscript in preparation.
-Madhun AS, Jacobsen H, Cox RJ, Haaheim LR. Combining the use of whole and split virus vaccine formulations in mouse model as an alternative prime-boost vaccination strategy. Manuscript in preparation.
-Madhun AS, Akselsen PA, Sjursen H, Smith I, Pedersen G, Svindland S, Nøstbakken JK, Nilsen M, Jul-Larsen Å, Major D, Wood J, Cox RJ. An adjuvanted pandemic influenza H1N1 vaccine provides early protection in health care workers. Submitted.
-Haaheim LR, Madhun AS, Cox R. Pandemic Influenza Vaccines – The Challenges. Viruses 2009: 1(3): DOI 10.3390/v1031089
-Madhun AS, Haaheim LR, Nilsen MV, Cox RJ. Intramuscular Matrix-M-adjuvanted virosomal H5N1 vaccine induces high frequencies of multifunctional Th1 CD4+ cells and strong antibody responses in mice. Vaccine. 2009; 27:7367-76
-Hauge S, Madhun AS, Major D, Brokstad KA, Vogel FR, Zambon M, Wood J, Haaheim LR, Cox RJ. The immunogenicity of a cell-derived H7N1 split influenza virion vaccine in mice. Scand J Immunol. 2009; 69:576-8.
-Cox RJ, Madhun AS, Hauge S, Sjursen H, Major D, Kuhne M, Höschler K, Saville M, Vogel FR, Barclay W, Donatelli I, Zambon M, Wood J, Haaheim LR. A phase I clinical trial of a PER.C6 cell grown influenza H7 virus vaccine. Vaccine. 2009; 27:1889-97.
-Cox RJ, Major D, Hauge S, Madhun AS, Brokstad KA, Kuhne M, Smith J, Vogel FR, Zambon M, Haaheim L, Wood J. A cell-based H7N1 split influenza virion vaccine confers protection in a mouse and ferret challenge models. Influenza Other Respi Viruses 2009; 3:107-17.
-Hauge S, Madhun AS, Cox RJ, Brokstad KA, Haaheim LR. A comparison of the humoral and cellular immune responses at different immunological sites after split influenza virus vaccination of mice. Scand J Immunol 2007; 65: 14-21.
-Hauge S, Madhun A, Cox RJ, Haaheim LR. Quality and kinetics of the antibody response in mice after three different low-dose influenza virus vaccination strategies. Clin Vaccine Immunol 2007; 14:978-83.
-Cox RJ, Haaheim LR, Ericsson JC, Madhun AS, Brokstad KA. The humoral and cellular responses induced locally and systemically after parenteral influenza vaccination in man. Vaccine 2006; 24:6577-80.
-Szyszko E, Brokstad K, Cox RJ, Hovden AO, Madhun A, Haaheim LR. Impact of influenza vaccine formulation with a detailed analysis of the cytokine response. Scand J Immunol 2006; 64: 467-75.
-Cox RJ, Hovden AO, Brokstad KA, Szyszko E, Madhun AS, Haaheim LR. The humoral immune response and protective efficacy of vaccination with inactivated split and whole influenza virus vaccines in BALB/c mice. Vaccine 2006; 24: 6585-7.
-Madhun AS, Søreide A, Olofsson J, Cox RJ, Haaheim LR. Is influenza priming necessary to mount a mucosal immune response to parenteral influenza vaccination in small children? (Book Chapter) In: Options for the Control of Influenza III. Brown LE, Hampson AW, Webster RG, Eds. Elsevier Science B.V., Amsterdam, 1996, 113-8.
-Hovden AO, Cox RJ, Madhun AS, Haaheim LR. Two doses of parenterally administered split influenza virus vaccine elicited high serum IgG concentrations which effectively limited viral shedding upon challenge in mice. Scand J Immunol 2005; 62: 342-52.
-Madhun A, Cox R, Haaheim LR, Jonsson R, Brokstad KA. The kinetics of the systemic and local immune response to parentral influenza vaccination. (Book Chapter) In: Proceedings of the International Conference on options for the Control of Influenza V. Kawaoka Y, Ed. Elsevier B.V., Amsterdam, 2004, 515-8.
-Madhun AS, Cox RJ, Haaheim LR. Effect of age and natural priming on the IgG and IgA subclass responses after parenteral influenza vaccination. J Infect Dis 1999, 180; 1356-60.
-Madhun AS. Characteristics of the humoral immune response after parenteral influenza vaccination. Dr. Scient. thesis, University of Bergen 1998. ISBN 82-7653-014-1.
-Madhun AS, Cox RJ, Søreide A, Olofsson J, Haaheim LR. Systemic and mucosal immune responses in young children and adults after parenteral influenza vaccination. J Infect Dis 1998. 178: 933-9.
-Madhun AS, Cox RJ, Seime A, Søvik O, Haaheim LR. Systemic and local immune responses after parenteral influenza vaccination in juvenile diabetic patients and healthy controls: results from a pilot study. Vaccine 1997; 16: 156-60.
-Madhun AS, Søreide A, Olofsson J, Cox RJ, Haaheim LR. Is influenza priming necessary to mount a mucosal immune response to parenteral influenza vaccination in small children? (Book Chapter) In: Options for the Control of Influenza III. Brown LE, Hampson AW, Webster RG, Eds. Elsevier Science B.V., Amsterdam, 1996, 113-8.
-Seime A, Madhun AS, Haaheim LR. Influensa vaksinering av diabetikere. Diabetikeren 1995; 6: 28-30.
 

Scientific meetings
-More than 35 oral or poster presentations in international and national scientific meetings.

Journal reviewer
A peer reviewer for the European Journal of Immunology, Vaccine, Scandinavian Journal of Immunology and Journal of Infectious Diseases.
 

Teaching and supervision experience:
-Supervising and co-supervising Master and PhD students at the University of Bergen.
-Teaching in the university courses in the fields of immunology, virology, immunological methods and vaccines.
 

Organisational skills and competences
-Student representative (1991-1992) at the Academic Council in Faculty of Science at BirZeit University.
-Student representative (1996-1998) at the Centre for International Health at the Faculty of Medicine, University of Bergen.
-Employee deputy representative (2003-2005) at UNIFOB, the Department for basic medicine research