Marc Berntssen

Seniorforsker

Telefon: +4799487708
Avdeling: Fiskeernæring,Trygt fôr

Jeg har min en bakgrunn I biokjemi, dyr fysiologi og ekotoksikologi. Hos NIFES jobber jeg med kjemiske fremmedstoffer i akvafôr, med hoved fokus på effekter på fiskehelse og overføring til de spiselige deler av fisk.



Arbeidsområde
Utvalgte publikasjoner
Prosjekter
Vitenskaplige publikasjoner


1. Fôr-til muskel overføring av kjemiske kontaminanter


Om fremmedstoffer i fôret kan gir fare for matvaretrygghet er avhengig av deres emne til å overføres til de spiselige deler av fisk. Sammen med RIVM i Nederland har NIFES utviklet kompartment-fysiologiske modeller som beskrive overfôring og transformering av fremmedstoffer fra fôr til muskel.


[caption id="attachment_7238" align="aligncenter" width="300"]  Berntssen et al. 2013. Food Addit Contam Part A, 30, 1581-1589).
Berntssen et al. 2013. Food Addit Contam Part A, 30, 1581-1589).[/caption]



2. Fremmedstoffer I fôr påvirker fiskes helse


Vi bruker biomarkører, som for eksempel celle deling i tarmen, for å bestemme effektnivåer av fremmedstoffer i fiskefôr som kan gir muligens påvirke fiskes helse.


[caption id="attachment_7240" align="aligncenter" width="300"]  Berntssen et al. 2004 Aquaculture Nutrition 10; 83-97.
Berntssen et al. 2004 Aquaculture Nutrition 10; 83-97.[/caption]


3.Nye fremmedstoffer i fiskefôr


Nye fôringredienser medfører også nye fremmedstoffer som før ikke har vært tilknyttet til oppdrett av fisk og som kan  påvirke fiskes helse og/ eller matvaretrygghet. Utfordringen i å identifiserer nye kontaminanter er mangfoldet av potensielle nye kontaminant grupper som kan finnes i de nye fôringredienser (f. eks. pesticider, medisinrester, mykotoksiner). Sammen med IUPA i Spania skreener vi for fremmedstoffer i nye fôringredienser og deres overfôring i den akvatiske matproduksjonskjede.


Utvalgte publokasjoner (fra >65)

Nacher-Mestre, J., Serrano, R., Portoles, T., Berntssen, M. H. G., Perez-Sanchez, J. & Hernandez, F. (2014) Screening of pesticides and polycyclic aromatic hydrocarbons in feeds and fish tissues by gas chromatography coupled to high-resolution mass spectrometry using atmospheric pressure chemical ionization. J. Agric. Food Chem., 62, 2165-2174.

Liland, N. S., Rosenlund, G., Berntssen, M. H. G., Brattelid, T., Madsen, L. & Torstensen, B. E. (2013) Net production of Atlantic salmon (FIFO, Fish in Fish out < 1) with dietary plant proteins and vegetable oils. Aquac. Nutr., 19, 289-300.

Berntssen, M. H. G., Lock, E. J., Zeilmaker, M. J. & Van Eijkeren, J. C. H. (2013) Toxicokinetic model assessment on the dechlorination of dietary toxaphene CHB-62 into CHB-44 in Atlantic salmon (Salmo salar L.). Food Additives and Contaminants Part a-Chemistry Analysis Control Exposure & Risk Assessment, 30, 1581-1589.

Berntssen, M. H. G., Lundebye, A. K., Hop-Johannessen, L. & Lock, E. J. (2012) Dechlorination of the dietary nona-chlorinated toxaphene congeners 62 and 50 into the octa-chlorinated toxaphene congeners 44 and 40 in zebrafish (Danio rerio) and Atlantic salmon (Salmo salar). Aquat. Toxicol., 112, 54-61.

Berntssen, M. H. G., Valdersnes, S., Rosenlund, G., Torstensen, B. E., Zeilmaker, M. J. & van Eijkeren, J. C. H. (2011) Toxicokinetics and carry-over model of alpha-hexabromocyclododecane (HBCD) from feed to consumption-sized Atlantic salmon (Salmo salar) Food Additives and Contaminants, 28, 1274-1286.

Berntssen, M. H. G., Olsvik, P. A., Torstensen, B. E., Julshamn, K., Midtun, T., Goksoyr, A., Johansen, J., Sigholt, T., Joerum, N., Jakobsen, J. V., Lundebye, A. K. & Lock, E. J. (2010b) Reducing persistent organic pollutants while maintaining long chain omega-3 fatty acid in farmed Atlantic salmon using decontaminated fish oils for an entire production cycle. Chemosphere, 81, 242-252.

Berntssen, M. H. G., Julshamn, K. & Lundebye, A. K. (2010a) Chemical contaminants in aquafeeds and Atlantic salmon (Salmo salar) following the use of traditional- versus alternative feed ingredients. Chemosphere, 78, 637-646.

Berntssen, M. H. G., Giskegjerde, T. A., Rosenlund, G., Torstensen, B. E. & Lundebye, A. K. (2007) Predicting world health organization toxic equivalency factor dioxin and dioxin-like polychlorinated biphenyl levels in farmed Atlantic salmon (Salmo salar) based on known levels in feed. Environ. Toxicol. Chem., 26, 13-23.

Berntssen, M. H. G., Lundebye, A. K. & Torstensen, B. E. (2005) Reducing the levels of dioxins and dioxin-like PCBs in farmed Atlantic salmon by substitution of fish oil with vegetable oil in the feed. Aquac. Nutr., 11, 219-231.

Berntssen, M. H. G., Hylland, K., Julshamn, K., Lundebye, A. K. & Waagbo, R. (2004a) Maximum limits of organic and inorganic mercury in fish feed. Aquac. Nutr., 10, 83-97.

Berntssen, M. H. G., Hylland, K., Lundebye, A. K. & Julshamn, K. (2004b) Higher faecal excretion and lower tissue accumulation of mercury in Wistar rats from contaminated fish than from methylmercury chloride added to fish. Food Chem. Toxicol., 42, 1359-1366.

Berntssen, M. H. G., Aatland, A. & Handy, R. D. (2003) Chronic dietary mercury exposure causes oxidative stress, brain lesions, and altered behaviour in Atlantic salmon (Salmo salar) parr. Aquat. Toxicol., 65, 55-72.

Berntssen, M. H. G., Aspholm, O. O., Hylland, K., Bonga, S. E. W. & Lundebye, A. K. (2001) Tissue metallothionein, apoptosis and cell proliferation responses in Atlantic salmon (Salmo salar L.) parr fed elevated dietary cadmium. Comp. Biochem. Physiol. C-Toxicol. Pharmacol., 128, 299-310.

Amlund, H., Ingebrigtsen, K., Hylland, K., Ruus, A., Eriksen, D. O. & Berntssen, M. H. G. (2006) Disposition of arsenobetaine in two marine fish species following administration of a single oral dose of [C-14]arsenobetaine. Comp. Biochem. Physiol. C-Toxicol. Pharmacol., 143, 171-178.

  • 2015


    Jaime Nácher-Mestrea, Roque Serranoa, Eduardo Beltrán, Jaume Pérez-Sánchezc, Joana da Silva, Vasilis Karalazos, Félix Hernándeza, Marc Berntssen

    Occurrence and potential transfer of mycotoxins in gilthead sea bream and Atlantic salmon by use of novel alternative feed ingredients

    Chemosphere; Volum 128. S. 314-320
    • År: 2015

    Pål Asgeir Olsvik, Marc Berntssen, Liv Ingeborg Rosvoll Søfteland

    Modifying effects of vitamin E on chlorpyrifos toxicity in Atlantic salmon

    PLoS ONE; Volum 10.(3)
    • År: 2015

    Ole Jakob Nøstbakken, Helge Torbjørn Hove, Arne Duinker, Anne-Katrine L. Haldorsen, Marc Berntssen, Rita Hannisdal, Bjørn Tore Lunestad, Amund Måge, Lise Madsen, Bente Elisabeth Torstensen, Kåre Julshamn

    Contaminant levels in Norwegian farmed Atlantic salmon (Salmo salar) in the 13-year period from 1999 to 2011

    Environment International; Volum 74. S. 274-280
    • År: 2015

    Pål Asgeir Olsvik, Marc Berntssen, Rune Waagbø, Ernst Morten Hevrøy, Liv Ingeborg Rosvoll Søfteland

    The mining chemical Polydadmac is cytotoxic but does not interferewith Cu-induced toxicity in Atlantic salmon hepatocytes

    Toxicology in Vitro; Volum 30. S. 492-505
    • År: 2015

    Liv Ingeborg Rosvoll Søfteland, Marc Berntssen, Jennifer A. Kirwan, Trond Røvik Størseth, Mark.R. Viant, Bente Elisabeth Torstensen, Rune Waagbø, Pål Asgeir Olsvik

    Omega-3 and alpha-tocopherol provide more protection against contaminants in novel feeds for Atlantic salmon (Salmo salar L.) than omega-6 and gamma tocopherol

    Toxicology reports;
    • År: 2015
  • 2014


    Jaime Nacher-Mestre, Roque Serrano,, Tania Portoles, Marc Berntssen, Jaume Perez-Sanchez, Felix Hernadez

    Screening of pesticides and polycyclic aromatic hydrocarbons in feeds and fish tissues by gas chromatography coupled to high-resolution mass spectrometry using atmospheric pressure chemical ionization

    Journal of Agricultural and Food Chemistry; Volum 62.(10) S. 2165-2174
    • År: 2014

    Marc Berntssen, Stig Valdersnes, Bjørn Tore Lunestad, Bjarne Hatlen, Martin Alm, Rune Waagbø, Louise Buttle

    Residue levels of enrofloxacin and ciprofloxacin in processed animal by-products used in Atlantic salmon feeds and their long-term carry-over to the edible part of the fish

    Aquaculture Nutrition;
    • År: 2014

    Liv Ingeborg Rosvoll Søfteland, Jennifer A. Kirwan, Tiago S.F. Hori, Trond Røvik Størseth, Ulf Sommer, Marc Berntssen, Mark.R. Viant, Matthew L. Rise, Rune Waagbø, Bente Elisabeth Torstensen, Marije Booman, Pål Asgeir Olsvik

    Toxicological effect of single contaminants and contaminant mixtures associated with plant ingredients in novel salmon feeds

    Food and Chemical Toxicology; Volum 73. S. 157-174
    • År: 2014

    Nina Sylvia Liland, Adam C. Simonsen, Lars Duelund, Bente Elisabeth Torstensen, Marc Berntssen, Ole G. Mouritsen

    Polyaromatic hydrocarbons do not disturb liquid-liquid phase coexistence, but increase the fluidity of model membranes

    Chemistry and Physics of Lipids; Volum 184. S. 18-24
    • År: 2014
  • 2013


    Nina Sylvia Liland, Grethe Rosenlund, Marc Berntssen, Trond Brattelid, Lise Madsen, Bente Elisabeth Torstensen

    Net production of Atlantic salmon (FIFO, Fish in Fish out < 1) with dietary plant proteins and vegetable oils

    Aquaculture Nutrition; Volum 19.(3) S. 289-300
    • År: 2013

    Veronika Sele, Heidi Amlund, Marc Berntssen, Jannicke Alling Bakkejord, Kasper Skov, Jens Jørgen Sloth

    Detection of arsenic-containing hydrocarbons in a range of commercial fish oils by GC-ICPMS analysis

    Analytical and Bioanalytical Chemistry; Volum 405.(15) S. 5179-5190
    • År: 2013

    Marc Berntssen, Erik-Jan Lock, Marco J. Zeilmaker, Jan C.H. van Eijkeren

    Toxicokinetic model assessment on the dechlorination of dietary toxaphene CHB-62 into CHB-44 in Atlantic salmon (Salmo salar L.)

    Food Additives & Contaminants; Volum 30.(9) S. 1581-1589
    • År: 2013

    Kåre Julshamn, Arne Duinker, Marc Berntssen, Bente Merete Nilsen, Sylvia Frantzen, Kjell Harald Nedreaas, Amund Måge

    A baseline study on levels of polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, non-ortho and mono-ortho PCBs, non-dioxin-like PCBs and polybrominated diphenyl ethers in Northeast Arctic cod (Gadus morhua) from different parts of the Barents Sea

    Marine Pollution Bulletin; Volum 75.(1-2) S. 250-258
    • År: 2013

    Rune Waagbø, Marc Berntssen, Trine Danielsen, Hege Hellberg, Anna Lena Kleppa, Trygve Berg Lea, Grethe Rosenlund, Leif Tvenning, S. Susort, Vibeke Vikeså, Olav Breck

    Feeding Atlantic salmon diets with plant ingredients during the seawater phase - a full-scale net production of marine protein with focus on biological performance, welfare, product quality and safety

    Aquaculture Nutrition; Volum 19.(4) S. 598-618
    • År: 2013
  • 2012


    Marc Berntssen, Anne-Katrine L. Haldorsen, Lene Hop Johannessen, Erik-Jan Lock

    Dechlorination of the dietary nona-chlorinated toxaphene congeners 62 and 50 into the octa-chlorinated toxaphene congeners 44 and 40 in zebrafish (Danio rerio) and Atlantic salmon (Salmo salar)

    Aquatic Toxicology; Volum 112. S. 54-61
    • År: 2012

    J. G. Bell, J. Dick, Fiona Strachan, D Guy, Marc Berntssen, M. Sprague

    Complete replacement of fish oil with a blend of vegetable oils affects dioxin, dioxin-like polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in 3 Atlantic salmon (Salmo salar) families differing in flesh adiposity

    Aquaculture; Volum 324. S. 118-126
    • År: 2012

    Pål Asgeir Olsvik, Marc Berntssen, Ketil Hylland, Dag Ø. Eriksen, Elisabeth Holen

    Low impact of exposure to environmentally relevant doses of Ra-226 in Atlantic cod (Gadus morhua) embryonic cells

    Journal of Environmental Radioactivity; Volum 109. S. 84-93
    • År: 2012
  • 2011


    Lennart Balk, Ketil Hylland, Tomas Hansson, Marc Berntssen, Jonny Beyer, Grete Jonsson, Alf Glein Melbye, Merete Grung, Bente Elisabeth Torstensen, Jan Fredrik Børseth, Halldora Skarphedinsdottir, Jarle Klungsøyr

    Biomarkers in Natural Fish Populations Indicate Adverse Biological Effects of Offshore Oil Production

    PLoS ONE; Volum 6.(5)
    • År: 2011

    Erik-Jan Lock, Per Gunnar Fjelldal, Bente Elisabeth Torstensen, Marit Bjørnevik, Olav Breck, J. Johansen, P. Reynolds, Trygve Sigholt, Nanne Joerum, Jan Vidar Jakobsen, Kari Ruohonen, Rune Waagbø, Marc Berntssen

    Dietary decontaminated fish oil has no negative impact on fish performance, flesh quality or production-related diseases in Atlantic salmon (Salmo salar)

    Aquaculture Nutrition; Volum 17.(3) S. E760-E772
    • År: 2011

    Marc Berntssen, Amund Måge, Kåre Julshamn, Britt Elin Rolfsnes, Anne-Katrine L. Haldorsen

    Carry-over of dietary organochlorine pesticides, PCDD/Fs, PCBs, and brominated flame retardants to Atlantic salmon (Salmo salar L.) fillets

    Chemosphere; Volum 83.(2) S. 95-103
    • År: 2011