Lise Madsen

Forskningssjef
Telefon: 41476177
Avdeling: Sjømat i modellsystem

Curriculum Vitae

Long standing expertise in combining animal studies with in vitro molecular biological studies to investigate how different nutritional and toxicological components in seafood interact, and the consequences of such interaction. During the recent years, a special interest in the association between the gut microbiome and metabolic health. Co-headed an extensive project to prepare a catalogue of the mouse gut metagenome (published in Nature Biotechnology) and afterwards involved in preparations of catalogues of the metagenome in pig, chicken, ruminant, macaques, salmon and whale. Further, the group is part of annual monitoring measures to map the content of illegal and undesirable substances in wild fish, farmed fish and seafood products.

Publikasjoner

Faglige foredrag

2012

Weight cycling affects adipose tissue genes involved in circadian rhythm and lipid metabolism

Simon E Nitter Dankel, Eirik Magnus Meek Degerud, Even Fjære, Christine Haugen, Jørn V. Sagen, Gunnar Mellgren, Lise Madsen

Vitenskapelige artikler (NVI)

2018

Factors influencing risk assessments of brominated flame-retardants; evidence based on seafood from the North East Atlantic Ocean

Ole Jakob Nøstbakken, Arne Duinker, Josef Daniel Rasinger, Bente Merete Nilsen, Monica Sanden, Sylvia Frantzen, Helge Torbjørn Hove, Anne-Katrine Lundebye, Marc Berntssen, Rita Hannisdal, Lise Madsen, Amund Måge
Environment International 119 p. 544-557
2018

Effects of frozen storage on phospholipid content in atlantic cod fillets and the influence on diet-induced obesity in mice

Kristin Røen Fauske, Annette Bernhard, Even Fjære, Lene Secher Myrmel, Livar Frøyland, Karsten Kristiansen, Bjørn Liaset, Lise Madsen
Nutrients 10:695 p. 1-17
2018

Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice

Annette Bernhard, Josef Daniel Rasinger, Helene Wisløff, Øyvor Kolbjørnsen, Lene Secher Myrmel, Marc Berntssen, Anne-Katrine Lundebye, Robin Ørnsrud, Lise Madsen
Food and Chemical Toxicology 118 p. 608-625
2018

CRISPR/cascade 9-mediated genome editing-challenges and opportunities

Bhaskar Roy, Jing Zhao, Chao Yang, Wen Luo, Teng Xiong, Yong Li, Xiaodong Fang, Guanjun Gao, Chabungbam O Singh, Lise Madsen, Yong Zhou, Karsten Kristiansen
Frontiers in Genetics 9
2017

Increased microvascular permeability in mice lacking Epac1 (Rapgef3)

Reidun Kristin Kopperud, Cecilie Brekke Rygh, Tine Veronica Karlsen, Camilla Krakstad, Rune Kleppe, Erling Andre Høivik, Marit Bakke, Olav Tenstad, Frode Selheim, Åsa Liden, Lise Madsen, Tina Pavlin, Torfinn Taxt, k kristiansen, FE Curry, Rolf K. Reed, Stein Ove Doskeland
Acta Physiologica 219 p. 441-452
2017

Lower levels of Persistent Organic Pollutants, metals and the marine omega 3-fatty acid DHA in farmed compared to wild Atlantic salmon (Salmo salar)

Anne-Katrine L. Haldorsen, Erik-Jan Lock, Josef Daiel Rasinger, Ole Jakob Nøstbakken, Rita Hannisdal, Egil Karlsbakk, Vidar Wennevik, Abdullah Sami Madhun, Lise Madsen, Ingvild Eide Graff, Robin Ørnsrud
Environmental Research 155 p. 49-59
2017

Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydrates

Anne-Marie Lundsgaard, Andreas M. Fritzen, Kim A. Sjøberg, Lene Secher Myrmel, Lise Madsen, Jørgen F.P. Wojtaszewski, Erik A. Richter, Bente Kiens
Molecular Metabolism 6 p. 22-29
2017

Visualization and quantification of browning using a Ucp1-2A-luciferase knock-in mouse model

Liufeng Mao, Baoming Nie, Tao Nie, Xiaoyan Hui, Xuefei Gao, Xiaoliang Lin, Xin Liu, Yong Xu, Xiaofeng Tang, Ran Yuan, Kuai Li, Peng Li, Ke Ding, Yu Wang, Aimin Xu, Jian Fei, Weiping Han, Pentao Liu, Lise Madsen, Karsten Kristiansen, Zhiguang Zhou, Sheng Ding, Donghai Wu
Diabetes 66 p. 407-417
2017

Two distinct metacommunities characterize the gut microbiota in Crohn's disease patients

Qing He, Yuan Gao, Zhuye Jie, Xinlei Yu, Janne Marie Laursen, Liang Xiao, Ying Li, Lingling Li, Faming Zhang, Qiang Feng, Xiaoping Li, Jinghong Yu, Chuan Liu, Ping Lan, Ting Yan, Xin Liu, Xun Xu, Huanming Yang, Jian Wang, Lise Madsen, Susanne Brix, Jianping Wang, Karsten Kristiansen, Huijue Jia
GigaScience 6
2017

The gut microbiome in atherosclerotic cardiovascular disease

Zhuye Jie, Huihua Xia, Shi-Long Zhong, Qiang Feng, Shenghui Li, Suisha Liang, Huanzi Zhong, Zhipeng Liu, Yuan Gao, Hui Zhao, Dongya Zhang, Zheng Su, Zhiwei Fang, Zhou Lan, Junhua Li, Liang Xiao, Jun Li, Ruijun Li, Xiaoping Li, Fei Li, Huahui Ren, Yan Huang, Yangqing Peng, Guanglei Li, Bo Wen, Bo Dong, Ji-Yan Chen, Qing-Shan Geng, Zhi-Wei Zhang, Huanming Yang, Jian Wang, Jun Wang, Xuan Zhang, Lise Madsen, Susanne Brix, Guang Ning, Xun Xu, Xin Liu, Yong Hou, Huijue Jia, Kunlun He, Karsten Kristiansen
Nature Communications 8:845 p. 1-12
2017

The microbiota continuum along the female reproductive tract and its relation to uterine-related diseases

Chen Chen, Xiaolei Song, Weixia Wei, Huanzi Zhong, Juanjuan Dai, Zhou Lan, Fei Li, Xinlei Yu, Qiang Feng, Zirong Wang, Hailiang Xie, Xiaomin Chen, Chunwei Zeng, Bo Wen, Liping Zeng, Hui Du, Huiru Tang, Changlu Xu, Yan Xia, Huihua Xia, Huanming Yang, Jian Wang, Jun Wang, Lise Madsen, Susanne Brix, Karsten Kristiansen, Xun Xu, Junhua Li, Ruifang Wu, Huijue Jia
Nature Communications 8
2017

A safflower oil based high-fat/high-sucrose diet modulates the gut microbiota and liver phospholipid profiles associated with early glucose intolerance in the absence of tissue inflammation

Niels Banhos Danneskiold-Samsøe, Daniel Andersen, Ilinca Daria Radulescu, Ann Normann-Hansen, Asker Brejnrod, Marie Kragh, Tobias Madsen, Christian Nielsen, Knud Josefsen, Xavier Frette, Even Fjære, Lise Madsen, Lars I Hellgren, Susanne Brix, Karsten Kristiansen
61
2017

Dietary intake and adipose tissue content of long-chain n-3 PUFAs and subsequent 5-y change in body weight and waist circumference

Marianne U. Jakobsen, Lise Madsen, Flemming Skjoth, Tina Landsvig Berentzen, Jytte Halkjær, Anne Tjønneland, Erik B. Schmidt, Thorkild I A Sørensen, Karsten Kristiansen, Kim Overvad
American Journal of Clinical Nutrition 105 p. 1148-1157
2017

Induction of lipogenesis in white fat during cold exposure in mice: Link to lean phenotype

P Flachs, K Adamcova, P Zouhar, C Marques, Petra Janovská, I Viegas, JG Jones, Kristina Bardová, M Svobodova, J Hansikova, Ondrej Kuda, Martin Rossmeisl, Ulrike Liisberg, Alison G. Borkowska, K Kristiansen, Lise Madsen, J Kopecky
International Journal of Obesity 41 p. 372-380
2017

Links between dietary protein sources, the gut microbiota, and obesity

Lise Madsen, Lene Secher Myrmel, Even Fjære, Bjørn Liaset, Karsten Kristiansen
Frontiers in Physiology 8
2017

Lipidomic profiling reveals distinct differences in plasma lipid composition in healthy, prediabetic, and type 2 diabetic individuals

Huanzi Zhong, Chao Fang, Yanqun Fan, Yan Lu, Bo Wen, Huahui Ren, Guixue Hou, Fangming Yang, Hailiang Xie, Zhuye Jie, Ye Peng, Zhiqiang Ye, Jiegen Wu, Jin Zi, Guoqing Zhao, Jiayu Chen, Xiao Bao, Yihe Hu, Yan Gao, Jun Zhang, Huanming Yang, Jian Wang, Lise Madsen, Karsten Kristiansen, Chuanming Ni, Junhua Li, Siqi Liu
GigaScience 6
2017

Analyses of gut microbiota and plasma bile acids enable stratification of patients for antidiabetic treatment

Yanyun Gu, Xiaokai Wang, Junhua Li, Yifei Zhang, Huanzi Zhong, Ruixin Liu, Dongya Zhang, Qiang Feng, Xiaoyan Xie, Jie Hong, Huahui Ren, Wei Liu, Jing Ma, Qing Su, Hongmei Zhang, Jialin Yang, Xiaoling Wang, Xinjie Zhao, Weiqiong Gu, Yufang Bi, Yongde Peng, Xiaoqiang Xu, Huihua Xia, Fang Li, Xun Xu, Huanming Yang, Guowang Xu, Lise Madsen, Karsten Kristiansen, Guang Ning, Weiqing Wang
Nature Communications 8
2017

Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention

Ruixin Liu, Jie Hong, Xiaoqiang Xu, Qiang Feng, Dongya Zhang, Yanyun Gu, Juan Shi, Shaoqian Zhao, Wen Liu, Xiaokai Wang, Huihua Xia, Zhipeng Liu, Bin Cui, Peiwen Liang, Liuqing Xi, Jiabin Jin, Xiayang Ying, Xiaolin Wang, Xinjie Zhao, Wanyu Li, Huijue Jia, Zhou Lan, Fengyu Li, Rui Wang, Yingkai Sun, Minglan Yang, Yuxin Shen, Zhuye Jie, Junhua Li, Xiaomin Chen, Huanzi Zhong, Hailiang Xie, Yifei Zhang, Weiqiong Gu, Xiaxing Deng, Baiyong Shen, Xun Xu, Huanming Yang, Guowang Xu, Yufang Bi, Shenghan Lai, Jian Wang, Lu Qi, Lise Madsen, Jiqiu Wang, Guang Ning, Karsten Kristiansen, Weiqing Wang
Nature Medicine 23 p. 859-868
2017

High-fat feeding rather than obesity drives taxonomical and functional changes in the gut microbiota in mice

Liang Xiao, Si Brask Sonne, Qiang Feng, Ning Chen, Zhongkui Xia, Xiaoping Li, Zhiwei Fang, Dongya Zhang, Even Fjære, Lisa Kolden Midtbø, Muriel Derrien, Floor Hugenholtz, Longqing Tang, Junhua Li, Jianfeng Zhang, Chuan Liu, Qin Hao, Ulla Birgitte Vogel, Alicja Mortensen, Michiel Kleerebezem, Tine Rask Licht, Huanming Yang, Jian Wang, Yingrui Li, Manimozhiyan Arumugam, Jun Wang, Lise Madsen, Karsten Kristiansen
Microbiome 5
2017

Opposite regulation of insulin sensitivity by dietary lipid versus carbohydrate excess

Anne-Marie Lundsgaard, Kim A. Sjøberg, Louise D Høeg, Jacob Jeppesen, Andreas B Jordy, Annette K. Serup, Andreas M. Fritzen, Henriette Pilegaard, Lene Secher Myrmel, Lise Madsen, Jørgen F.P. Wojtaszewski, Erik A. Richter, Bente Kiens
Diabetes 66 p. 2583-2595
2017

Obesity is associated with depot-specific alterations in adipocyte DNA methylation and gene expression

Si Brask Sonne, Rachita Yadav, Guangliang Yin, Marlene D. Dalgaard, Lene Secher Myrmel, Ramneek Gupta, Jun Wang, Lise Madsen, Shingo Kajimura, Karsten Kristiansen
Adipocyte 6 p. 124-133
2016

Lean seafood intake reduces postprandial c-peptid and lactate concentrations in healthy adults in a randomized controlled trial with a crossover design

Eli Kristin Aadland, Ingvild Eide Graff, Charles Lavigne, Øyvin Andre Solberg Eng, Martine Paquette, Asle Holthe, Gunnar Mellgren, Lise Madsen, Hélène Jacques, Bjørn Liaset
Journal of Nutrition 146 p. 1027-1034
2016

The elusive endogenous adipogenic PPARγ agonists: Lining up the suspects

Philip Hallenborg, Rasmus K. Petersen, Irene Kouskoumvekaki, John W. Newman, Lise Madsen, Karsten Kristiansen
Progress in lipid research 61 p. 149-162
2016

Long-term consumption of an obesogenic high fat diet prior to ischemia-reperfusion mediates cardioprotection via Epac1-dependent signaling

Ravn Fritdtjov Edland, Anita Wergeland, Reidun Kristin Kopperud, Kathrine Sivertsen åsrud, Erling Andre Høivik, Solveig Lund Witsø, Reidun Æsøy, Lise Madsen, K Kristiansen, Marit Bakke, Stein Ove Doskeland, Anne K Jonassen
13 p. 1-11
2016

Marine fatty acids aggravate hepatotoxicity of α-HBCD in juvenile female BALB/c mice

Annette Bernhard, Marc Berntssen, Anne-Katrine L. Haldorsen, Anita Røyneberg Alvheim, Lene Secher Myrmel, Even Fjære, Bente Elisabeth Torstensen, Karsten Kristiansen, Lise Madsen, Trond Brattelid, Josef Daniel Rasinger
Food and Chemical Toxicology 97 p. 411-423
2016

A reference gene catalogue of the pig gut microbiome

Liang Xiao, Jordi Estelle, Pia Kiilerich, Yuliaxis Ramayo-Caldas, Zhongkui Xia, Qiang Feng, Suisha Liang, Annioyan Pedersen, Niels Jorgen Kjeldsen, Chuan Liu, Emmanuelle Maguin, Joël Doré, Nicolas Pons, Emmanuelle Le Chatelier, Edi Prifti, Junhua Li, Huijue Jia, Xin Liu, Xun Xu, Stanislav D. Ehrlich, Lise Madsen, Karsten Kristiansen, Claire Rogel-Gaillard, Jun Wang
Nature Microbiology 1:16161
2016

Macronutrient composition determines accumulation of persistent organic pollutants from dietary exposure in adipose tissue of mice

Lene Secher Myrmel, Even Fjære, Lisa Kolden Midtbø, Annette Bernhard, Rasmus Koefoed Petersen, Si Brask Sonne, Alicja Mortensen, Qin Hao, Trond Brattelid, Bjørn Liaset, Karsten Kristiansen, Lise Madsen
Journal of Nutritional Biochemistry 27 p. 307-316
2016

P53 regulates expression of uncoupling protein 1 through binding and repression of PPARγ coactivator-1α

Philip Hallenborg, Even Fjære, Bjørn Liaset, Rasmus Koefoed Petersen, Incoronata Murano, Si Brask Sonne, Mathias Falkerslev, Sally Winther, Benjamin Anderschou Holbech Jensen, Tao Ma, Jacob B. Hansen, Saverio Cinti, Blagoy Blagoev, Lise Madsen, Karsten Kristiansen
American Journal of Physiology. Endocrinology and Metabolism 310 p. E116-E128
2016

Diet-induced obesity, energy metabolism and gut microbiota in C57BL/6J mice fed Western diets based on lean seafood or lean meat mixtures

Jacob Bak Holm, Alexander Rønnevik, Hanne Sørup Tastesen, Even Fjære, Kristin Røen Fauske, Ulrike Liisberg, Lise Madsen, Karsten Kristiansen, Bjørn Liaset
Journal of Nutritional Biochemistry 31 p. 127-136
2016

Dietary fat drives whole-body insulin resistance and promotes intestinal inflammation independent of body weight gain

Benjamin Anderschou Holbech Jensen, Thomas S. Nielsen, Andreas M. Fritzen, Jacob Bak Holm, Even Fjære, Annette K. Serup, Kamil Borkowski, Steve Risis, Simone I. Pærregaard, Ida Søgaard, Audrey Poupeau, Michelle Poulsen, Tao Ma, Christian Sina, Bente Kiens, Lise Madsen, Karsten Kristiansen, Jonas Thue Treebak
Metabolism: Clinical and Experimental 65 p. 1706-1719
2016

Effect of a long-term high-protein diet on survival, obesity development, and gut microbiota in mice

Pia Kiilerich, Lene Secher Myrmel, Even Fjære, Qin Hao, Floor Hugenholtz, Si Brask Sonne, Muriel Derrien, Lone Møller Pedersen, Rasmus Koefoed Petersen, Alicja Mortensen, Tine Rask Licht, Maria Unni Rømer, Ulla Birgitte Vogel, Linn Jeanette Waagbø, Natasa Giallourou, Qiang Feng, Liang Xiao, Chuan Liu, Bjørn Liaset, Michiel Kleerebezem, Jun Wang, Lise Madsen, Karsten Kristiansen
American Journal of Physiology. Endocrinology and Metabolism 310 p. E886-E899
2016

FFAR4 (GPR120) signaling is not required for anti-inflammatory and insulin-sensitizing effects of Omega-3 fatty acids

Simone Isling Pærregaard, Marianne Agerholm, Annette Karen Serup, Tao Ma, Bente Kiens, Lise Madsen, Karsten Kristiansen, Benjamin Anderschou Holbech Jensen
Mediators of Inflammation 2016:1536047 p. 1-12
2016

Intake of a Western diet containing cod instead of pork alters fatty acid composition in tissue phospholipids and attenuates obesity and hepatic lipid accumulation in mice

Ulrike Liisberg, Kristin Røen Fauske, Ondrej Kuda, Even Fjære, Lene Secher Myrmel, Nina Cecilie Norberg, Livar Frøyland, Ingvild Eide Graff, Bjørn Liaset, Karsten Kristiansen, Jan Kopecký, Lise Madsen
Journal of Nutritional Biochemistry 33 p. 119-127
2016

The protein source determines the potential of high protein diets to attenuate obesity development in C57BL/6J mice

Ulrike Liisberg, Lene Secher Myrmel, Even Fjære, Alexander Rønnevik, Susanne Bjelland, Kristin Røen Fauske, J Holm, Astrid L. Basse, JB Hansen, Bjørn Liaset, Karsten Kristiansen, Lise Madsen
Adipocyte 5 p. 196-211
2015

Contaminant levels in Norwegian farmed Atlantic salmon (Salmo salar) in the 13-year period from 1999 to 2011

Ole Jakob Nøstbakken, Helge Torbjørn Hove, Arne Duinker, Anne-Katrine L. Haldorsen, Marc Berntssen, Rita Hannisdal, Bjørn Tore Lunestad, Amund Måge, Lise Madsen, Bente Elisabeth Torstensen, Kåre Julshamn
Environment International 74 p. 274-280
2015

Chronic Trichuris muris infection decreases diversity of the intestinal microbiota and concomitantly increases the abundance of lactobacilli

Jacob Bak Holm, Daniel Sorobetea, Pia Kiilerich, Yuliaxis Ramayo-Caldas, Jordi Estellé, Tao Ma, Lise Madsen, Karsten Kristiansen, Marcus Svensson-Frej
PLoS ONE 10
2015

Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice

Lisa Kolden Midtbø, Alison G. Borkowska, Annette Bernhard, Alexander Rønnevik, Erik-Jan Lock, Michael L. Fitzgerald, Bente Elisabeth Torstensen, Bjørn Liaset, Trond Brattelid, Theresa L. Pedersen, John W. Newman, Karsten Kristiansen, Lise Madsen
Journal of Nutritional Biochemistry 26 p. 585-595
2015

Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism

Qin Hao, Rachita Yadav, Astrid L. Basse, Sidsel Petersen, Si B. Sonne, Simon Rasmussen, Qianhua Zhu, Zhike Lu, Jun Wang, Karine Audouze, Ramneek Gupta, Lise Madsen, Karsten Kristiansen, Jacob B. Hansen
American Journal of Physiology. Endocrinology and Metabolism 308 p. E380-E392
2015

Dynamics and stabilization of the human gut microbiome during the first year of life

Fredrik Bäckhed, Josefine Roswall, Yangqing Peng, Qiang Feng, Huijue Jia, Petia Kovatcheva-Datchary, Yin Li, Yan Xia, Hailiang Xie, Huanzi Zhong, Muhammad Tanweer Khan, Jianfeng Zhang, Junhua Li, Liang Xiao, Jumana Al-Aama, Dongya Zhang, Ying Shiuan Lee, Dorota Kotowska, Camilla Colding, Valentina Tremaroli, Ye Yin, Stefan Bergman, Xun Xu, Lise Madsen, Karsten Kristiansen, Jovanna Dahlgren, Wang Jun
Cell Host and Microbe 17 p. 690-703
2015

Intake of hydrolyzed casein is associated with reduced body fat accretion and enhanced phase II metabolism in obesity prone C57BL/6J mice

Morten Rahr Clausen, Xumin Zhang, Christian Clement Yde, Ditte Bruun Ditlev, Haldis Haukås Lillefosse, Lise Madsen, Karsten Kristiansen, Bjørn Liaset, Hanne Christine Bertram
PLoS ONE 10
2015

A catalog of the mouse gut metagenome

Liang Xiao, Qiang Feng, Suisha Liang, Si Brask Sonne, Zhongkui Xia, Xinmin Qiu, Xiaoping Li, Hua Long, Jianfeng Zhang, Dongya Zhang, Chuan Liu, Zhiwei Fang, Joyce Chou, Jacob Glanville, Qin Hao, Dorota Kotowska, Camilla Colding, Tine Rask Licht, Donghai Wu, Jun Yu, Joseph Jao Yiu Sung, Qiaoyi Liang, Junhua Li, Huijue Jia, Zhou Lan, Valentina Tremaroli, Piotr Dworzynski, H. Bjørn Nielsen, Fredrik Bäckhed, Joël Doré, Emmanuelle Le Chatelier, S. Dusko Ehrlich, John C. Lin, Manimozhiyan Arumugam, Jun Wang, Lise Madsen, Karsten Kristiansen
Nature Biotechnology 33 p. 1103-1108
2015

Dietary n-6 PUFA, carbohydrate:protein ratio and change in body weight and waist circumference: A follow-up study

Marianne U. Jakobsen, Lise Madsen, Claus Dethlefsen, Karen M. Due, Jytte Halkjær, Thorkild I.A. Sørensen, Karsten Kristiansen, Kim Overvad
Public Health Nutrition 18 p. 1317-1323
2015

Tissue inhibitor of matrix metalloproteinase-1 is required for high-fat diet-induced glucose intolerance and hepatic steatosis in mice

Even Fjære, Charlotte Andersen, Lene Secher Myrmel, Rasmus Koefoed Petersen, Jakob Bondo Hansen, Hanne Sørup Tastesen, Thomas Mandrup-Poulsen, Nils Brünner, Karsten Kristiansen, Lise Madsen, Maria Unni Rømer
PLoS ONE 10:e0132910
2015

Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

Yu Jun, Feng Qiang, Wong Sunny Hei, Zhang Dongya, Q Liang, Youwen Qin, Longqing Tang, H Zhao, Jan Stenvang, Yanli Li, Xiaokai Wang, X Xu, N. Chen, W Wu, Jumana Al-Aama, Hans Jørgen Nielsen, Pia Kiilerich, Benjamin Anderschou Holbech Jensen, Tung On Yau, Zhou Lan, Huijue Jia, Junhua Li, Liang Xiao, Thomas Yuen Tung Lam, Siew C Ng, A Cheng, Vincent Wai-Sun Wong, F. Chan, Xun Xu, Huanming Yang, Lise Madsen, Christian Datz, Herbert Tilg, Jian Wang, Nils Brünner, Karsten Kristiansen, Manimozhiyan Arumugam, Joseph Jao Yiu Sung, Jun Wang
Gut 66 p. 70-78
2014

Weight cycling promotes fat gain and altered clock gene expression in adipose tissue in C57BL/6J mice

Simon E Nitter Dankel, Eirik Magnus Meek Degerud, Kamil Borkowski, Even Fjære, Lisa Kolden Midtbø, Christine Haugen, Margit Solsvik, Ann Marie Lavigne, Bjørn Liaset, Jørn V. Sagen, Karsten Kristiansen, Gunnar Mellgren, Lise Madsen
American Journal of Physiology. Endocrinology and Metabolism 306 p. E210-E224
2014

Dietary linoleic acid elevates the endocannabinoids 2-AG and anandamide and promotes weight gain in mice fed a low fat diet

Anita Røyneberg Alvheim, Bente Elisabeth Torstensen, Yu Hong Lin, Haldis Haukås Lillefosse, Erik-Jan Lock, Lise Madsen, Livar Frøyland, Joseph R. Hibbeln, Marian Kjellevold Malde
Lipids 49 p. 59-69
2014

Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J mice

Even Fjære, Ulrike Liisberg Aune, Kristin Røen, Alison H. Keenan, Tao Ma, Kamil Borkowski, David M. Kristensen, Guy W Novotny, Thomas Mandrup-Poulsen, Brian D. Hudson, Graeme Milligan, Yannan Xi, John W. Newman, Fawaz G. Haj, Bjørn Liaset, Karsten Kristiansen, Lise Madsen
Journal of Biological Chemistry 289 p. 16032-16045
2014

Multi-block PCA and multi-compartmental study of the metabolic responses to intake of hydrolysed versus intact casein in C57BL/6J mice by NMR-based metabolomics

Christian Clement Yde, Morten Rahr Clausen, Ditte Bruun Ditlev, Haldis Haukås Lillefosse, Lise Madsen, Karsten Kristiansen, Bjørn Liaset, Hanne Christine Bertram
Metabolomics p. 1-12
2014

Scallop protein with endogenous high taurine and glycine content prevents high-fat, high-sucrose-induced obesity and improves plasma lipid profile in male C57BL/6J mice

Hanne Sørup Tastesen, Alison H. Keenan, Lise Madsen, Karsten Kristiansen, Bjørn Liaset
Amino Acids 46 p. 1659-1671
2014

Urinary loss of tricarboxylic acid cycle intermediates as revealed by metabolomics studies: An underlying mechanism to reduce lipid accretion by whey protein ingestion?

Haldis Haukås Lillefosse, Morten Rahr Clausen, Christian Clement Yde, Ditte Bruun Ditlev, Xumin Zhang, Zhen-yu Du, Hanne Christine Bertram, Lise Madsen, Karsten Kristiansen, Bjørn Liaset
Journal of Proteome Research 13 p. 2560-2570
2014

A mixture of cod and scallop protein reduces adiposity and improves glucose tolerance in high-fat fed male C57BL/6J mice

Hanne Sørup Tastesen, Alexander Rønnevik, Kamil Borkowski, Lise Madsen, Karsten Kristiansen, Bjørn Liaset
PLoS ONE 9
2014

Proteomic analysis of cAMP-mediated signaling during differentiation of 3 T3-L1 preadipocytes

Kamil Borkowski, Krzysztof Wrzesinski, Adelina Rogowska-Wrzesinska, Karine Audouze, Jesse Bakke, Rasmus Koefoed Petersen, Fawaz G. Haj, Lise Madsen, Karsten Kristiansen
Biochimica et Biophysica Acta - Proteins and Proteomics 1844 p. 2096-2107
2014

PPARγ ligand production is tightly linked to clonal expansion during initiation of adipocyte differentiation

Philip Hallenborg, Rasmus Koefoed Petersen, Søren Feddersen, Ulrik Sundekilde, Jacob B Hansen, Blagoy Blagoev, Lise Madsen, Karsten Kristiansen
Journal of Lipid Research 55 p. 2491-2500
2013

Intake of farmed atlantic salmon fed soybean oil increases insulin resistance and hepatic lipid accumulation in mice

Lisa Kolden Midtbø, Mohammad Madani Ibrahim, Lene Secher Myrmel, Ulrike Liisberg Aune, Anita Røyneberg Alvheim, Nina Sylvia Liland, Bente Elisabeth Torstensen, Grete Rosenlund, Bjørn Liaset, Trond Brattelid, Karsten Kristiansen, Lise Madsen
PLoS ONE 8
2013

Dietary eicosapentaenoic acid supplementation accentuates hepatic triglyceride accumulation in mice with impaired fatty acid oxidation capacity

Zhen-yu Du, Tao Ma, Bjørn Liaset, Alison H. Keenan, Pedro Araujo, Erik-Jan Lock, Laurent Demizieux, Pascal Degrace, Livar Frøyland, Karsten Kristiansen, Lise Madsen
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1831 p. 291-299
2013

Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice

Anita Røyneberg Alvheim, Bente Elisabeth Torstensen, Yu Hong Lin, Haldis Haukås Lillefosse, Erik-Jan Lock, Lise Madsen, Joseph R. Hibbeln, Marian Kjellevold Malde
British Journal of Nutrition 109 p. 1508-1517
2013

Oceans and Human Health (OHH): a European Perspective from the Marine Board of the European Science Foundation (Marine Board-ESF)

Michael N. Moore, Michael H. Depledge, Lora Fleming, Philipp Hess, David Lees, Paul Leonard, Lise Madsen, Richard Owen, Hans Pirlet, Jan Seys, Vitor Vasconcelos, Aldo Viarengo
Microbial Ecology 65 p. 889-900
2013

Net production of Atlantic salmon (FIFO, Fish in Fish out < 1) with dietary plant proteins and vegetable oils

Nina Sylvia Liland, Grethe Rosenlund, Marc Berntssen, Trond Brattelid, Lise Madsen, Bente Elisabeth Torstensen
Aquaculture Nutrition 19 p. 289-300
2013

ERR gamma Enhances UCP1 Expression and Fatty Acid Oxidation in Brown Adipocytes

Karen Dixen, Astrid L. Basse, Maria Murholm, Marie S. Isidor, Lillian H. L. Hansen, M. Christine H. Petersen, Lise Madsen, Natasa Petrovic, Jan Nedergaard, Bjørn Quistorff, Jacob B Hansen
Obesity 21 p. 516-524
2013

Hydrolyzed casein reduces diet-induced obesity in male C57BL/6J mice

Haldis Haukås Lillefosse, Hanne Sørup Tastesen, Zhen-yu Du, Ditte B. Ditlev, Frits Alan Thorsen, Lise Madsen, Karsten Kristiansen, Bjørn Liaset
Journal of Nutrition 143 p. 1367-1375
2012

Activation of protein kinase A and exchange protein directly activated by cAMP promotes adipocyte differentiation of human mesenchymal stem cells

Bingbong Jia, Lise Madsen, Rasmus Koefoed Petersen, Nathalie Techer, Reidun Kristin Kopperud, Tao Ma, Stein Ove Doskeland, Gérard Ailhaud, Jinfu Wang, EZ-Zoubir Amri, Karsten Kristiansen
PLoS ONE 7
2012

Mdm2 controls CREB-dependent transactivation and initiation of adipocyte differentiation

Philip Hallenborg, Søren Feddersen, Sarah Francoz, Incoronata Murano, Ulrik Sundekilde, R.K. Petersen, Vyacheslav Akimov, M.V. Olson, Guillermina Lozano, Saverio Cinti, Bjørn Tore Gjertsen, Lise Madsen, Jean-Christophe Marine, Blagoy Blagoev, Karsten Kristiansen
Cell Death and Differentiation 19 p. 1381-1389
2012

High-glycemic index carbohydrates abrogate the antiobesity effect of fish oil in mice

Qin Hao, Haldis Haukås Lillefosse, Even Fjære, Lene Myrmel, Lisa Midtbø, Ragnhild Helene Jarlsby, Tao Ma, Bingbing Jia, Rasmus K. Petersen, Si Brask Sonne, Andre Chwalibog, Livar Frøyland, Bjørn Liaset, Karstein Kristiansen, Lise Madsen
American Journal of Physiology. Endocrinology and Metabolism 302 p. E1097-E1112
2012

A comparative analysis of the intestinal metagenomes present in guinea pigs (Cavia porcellus) and humans (Homo sapiens)

Falk Hildebrand, Tine Ebersbach, Henrik B. Nielsen, Xiaoping Li, Si Brask Sonne, Marcelo Bertalan, Peter Dimitrov, Lise Madsen, Junjie Qin, Jun Wang, Jeroen Raes, Karsten Kristiansen, Tine R. Licht
BMC Genomics 13
2012

Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity

Anita Røyneberg Alvheim, Marian Kjellevold Malde, Douglas Osei-Hyiaman, Yu Hong Lin, Robert J. Pawlosky, Lise Madsen, Karsten Kristiansen, Livar Frøyland, Joseph R. Hibbeln
Obesity 20 p. 1984-1994
2012

Of mice and men: Factors abrogating the antiobesity effect of omega-3 fatty acids

Lise Madsen, Karsten Kristiansen
Adipocyte 1 p. 173-176
2011

Nutritional regulation of bile acid metabolism is associated with improved pathological characteristics of the metabolic syndrome

Bjørn Liaset, Qin Hao, Henry Jørgensen, Philip Hallenborg, Zhen-yu Du, Tao Ma, Hanns-Ulrich Marschall, Mogens Kruhøffer, Ruiqiang Li, Quibin Li, Christian Clement Yde, Gabriel Cabrera Criales, Hanne C. Bertram, Gunnar Mellgren, Erik Snorre Øfjord, Erik-Jan Lock, Marit Espe, Livar Frøyland, Lise Madsen, Karsten Kristiansen
Journal of Biological Chemistry 286 p. 28382-28395
2011

Depot-Dependent Effects of Adipose Tissue Explants on Co-Cultured Hepatocytes

Zhen-yu Du, Tao Ma, Erik-Jan Lock, Qin Hao, Karsten Kristiansen, Livar Frøyland, Lise Madsen
PLoS ONE 6
2011

Sucrose counteracts the anti-inflammatory effect of fish oil in adipose tissue and increases obesity development in mice

Tao Ma, Bjørn Liaset, Qin Hao, Rasmus Koefoed Petersen, Even Fjære, Ha Thi Ngo, Haldis Haukås Lillefosse, Stine Ringholm, Si Brask Sonne, Jonas Thue Treebak, Henriette Pilegaard, Livar Frøyland, Karsten Kristiansen, Lise Madsen
PLoS ONE 6
2011

Chronic Consumption of Farmed Salmon Containing Persistent Organic Pollutants Causes Insulin Resistance and Obesity in Mice

Mohammad Madani Ibrahim, Even Fjære, Erik-Jan Lock, Danielle Naville, Heidi Amlund, Emmanuelle Meugnier, Brigitte Le Battistoni, Livar Frøyland, Lise Madsen, Niels Jessen, Sten Lund, Hubert Vidal, Jérôme Ruzzin
PLoS ONE 6 p. e25170
2011

Transcriptional regulatory program in wild-type and retinoblastoma gene-deficient mouse embryonic fibroblasts during adipocyte differentiation

Robab Hakim-Weber, Anne-M Krogsdam, Claus Jørgensen, M Fischer, Andreas Prokesch, Juliane G Bogner-Strauss, SR Bornstein, Jacob B Hansen, Lise Madsen, Karsten Kristiansen, Z Trajanoski, Hubert Hackl
BMC Research Notes
2010

UCP1 Induction during Recruitment of Brown Adipocytes in White Adipose Tissue Is Dependent on Cyclooxygenase Activity

Lise Madsen, Lone M Pedersen, Haldis Haukås Lillefosse, Even Fjaere, Ingeborg Brønstad, Qin Hao, Rasmus Kofoed Petersen, Philip Hallenborg, Tao Ma, Rita De Matteis, HERNANDEZ PEDRO W ARAUJO, Josep Mercader, M Louisa Bonet, Jacob B Hansen, Barbara Cannon, Jan Nedergaard, Jun Wang, Saverio Cinti, Peter Voshol, Stein Ove Doskeland, Karsten Kristiansen
PLoS ONE 5
2010

Cold-induced brown adipocyte recruitment in mouse white fat depots is predominantly determined by white to brown adipocyte transdifferentiation

G Barbatelli, I Murano, Lise Madsen, Qi Hao, M.A. Jimenez, K Kristiansen, J.P GIACOBINO, R DE MATTEIS, S Cinti
American Journal of Physiology. Endocrinology and Metabolism 118 p. 464-471
2010

β-oxidation modulates metabolic competition between eicosapentaenoic acid and arachidonic acid regulating prostaglandin E2 synthesis in rat hepatocytes–Kupffer cells

ZHEN-YU DU, T Ma, Synnøve Winterthun, K. Kristiansen, Livar Frøyland, Lise Madsen
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1801 p. 526-536
2010

Epidermis-Type Lipoxygenase 3 Regulates Adipocyte Differentiation and Peroxisome Proliferator-Activated Receptor Activity

Philip Hallenborg, Claus Jørgensen, Rasmus K. Petersen, Søren Feddersen, HERNANDEZ PEDRO W ARAUJO, Patrick Markt, Thierry Langer, Gerhard Furstenberger, Peter Krieg, Arjen Koppen, Eric Kalkhoven, Lise Madsen, K Kristiansen
Molecular and Cellular Biology 30 p. 4077-4091
2010

ADD1/SREBP1c activates the PGC1-α promoter in brown adipocytes

Qin Hao, Jacob B Hansen, Rasmus K. Petersen, Philip Hallenborg, Claus Jørgensen, Saverio Cinti, Philip J. Larsen, Knut R. Steffensen, Haibo Wang, Sheila Collins, Jun Wang, J. Å. Gustafsson, Lise Madsen, Karsten Kristiansen
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1801 p. 421-429
2010

Persistent Organic Pollutant Exposure Leads to Insulin Resistance Syndrome

Jérôme Ruzzin, Rasmus Petersen, Emmanuelle Meugnier, Lise Madsen, ERIK-JAN LOCK, Haldis Haukås Lillefosse, Tao Ma, Sandra Pesenti, Si Brask Sonne, Troels Torben Marstrand, Marian Kjellevold Malde, ZHEN-YU DU, Carine Chavey, Lluis Fajas, Anne Katrine Lundebye-Haldorsen, Christian Lehn Brand, Hubert Vidal, Karsten Kristiansen, Livar Frøyland
Environmental Health Perspectives 118 p. 465-471
2010

beta-oxidation modulates metabolic competition between eicosapentaenoic acid and arachidonic acid regulating prostaglandin E-2 synthesis in rat hepatocytes-Kupffer cells

Zhen-yu Du, Tao Ma, Synnøve Winterthun, Karsten Kristiansen, Livar Frøyland, Lise Madsen
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1801 p. 526-536
2010

The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation

Giorgio Barbatelli, Incoronata Murano, Lise Madsen, Qin Hao, Maria A. Jimenez, Karsten Kristiansen, Jean-Paul Giacobino, Rita De Matteis, Saverio Cinti
American Journal of Physiology. Endocrinology and Metabolism 298 p. E1244-E1253
2010

The importance of dietary modulation of cAMP and insulin signaling in adipose tissue and the development of obesity

Lise Madsen, Karsten Kristiansen
Annals of the New York Academy of Sciences 1190 p. 1-14
2009

Fish protein hydrolysate elevates plasma bile acids and reduces visceral adipose tissue mass in rats

Bjørn Liaset, Lise Madsen, Qin Hao, Gabriel Cabrera Criales, Gunnar Mellgren, Hanns-Ulrich Marschall, Philip Hallenborg, Marit Espe, Livar Frøyland, Karsten Kristiansen
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1791 p. 254-262
2009

Dynamic Regulation of Genes Involved in Mitochondrial DNA Replication and Transcription during Mouse Brown Fat Cell Differentiation and Recruitment

Maria Murholm, Karen Dixen, Klaus Qvortrup, Lillian H. L. Hansen, EZ-Zoubir Amri, Lise Madsen, Giorgio Barbatelli, Bjørn Quistorff, Jacob B Hansen
PLoS ONE 4
2009

Haploinsufficiency of the retinoblastoma protein gene reduces diet-induced obesity, insulin resistance, and hepatosteatosis in mice

Josep Mercader, Joan Ribot, Incoronata Murano, Søren Feddersen, Saverio Cinti, Lise Madsen, Karsten Kristiansen, M. Luisa Bonet, Andreu Palou
American Journal of Physiology. Endocrinology and Metabolism 297 p. E184-E193
2009

The tumor suppressors pRB and p53 as regulators of adipocyte differentiation and function

Philip Hallenborg, Søren Feddersen, Lise Madsen, Karsten Kristiansen
Expert opinion on therapeutic targets 13 p. 235-246
2008

Long term treatment with tetradecylthioacetic acid improves the antioxidant status in obese Zucker (fa/fa) rats

Hege Wergedahl, Kjetil Berge, Pavol Bohov, Karl Johan Tronstad, Lise Madsen, Rolf Kristian Berge
Drug Metabolism Letters 2 p. 138-145
2008

Activation of liver X receptors prevents statin-induced death of 3T3-L1 preadipocytes

Lise Madsen, Rasmus Kofoed Petersen, Knut R. Steffensen, Lone Møller Pedersen, Philip Hallenborg, Tao Ma, Livar Frøyland, Stein Ove Doskeland, Jan-Åke Gustafsson, Karsten Kristiansen
Journal of Biological Chemistry 283 p. 22723-22736
2008

Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes

Rasmus Kofoed Petersen, Lise Madsen, Lone Møller Pedersen, Philip Hallenborg, Hanne Hagland, Kristin Viste, Stein Ove Doskeland, Karsten Kristiansen
Molecular and Cellular Biology 28 p. 3804-3816
2008

cAMP-dependent signaling regulates the adipogenic effect of n-6 polyunsaturated fatty acids

Lise Madsen, Lone Møller Pedersen, Bjørn Liaset, Tao Ma, Rasmus Kofoed Petersen, Sjoerd van den Berg, Jie Pan, Karin Müller-Decker, Erik D. Dülsner, Robert Kleemann, Teake Kooistra, Stein Ove Doskeland, Karsten Kristiansen
Journal of Biological Chemistry 283 p. 7196-7205
2008

Macronutrients and obesity: views, news and reviews

Lise Madsen, Bjørn Liaset, Karsten Kristiansen
Future Lipidology 3 p. 43-74
2005

Glucose-induced lipogenesis in pancreatic beta-cells is dependent on SREBP-1

Maria B Sandberg, Jakob Fridriksson, Lise Madsen, Vika Rishi, Charles Vinson, Holm A Holmsen, Rolf Kristian Berge, Susanne Mandrup
Molecular and Cellular Endocrinology 240 p. 94-106
2003

Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases

Rasmus K. Petersen, RK Petersen, Claus Jørgensen, Arild C. Rustan, C Jorgensen, Livar Frøyland, Karin Muller-Decker, L Froyland, Gerhard Furstenberger, K Muller-Decker, G Furstenberger, Rolf Kristian Berge, Karsten Kristiansen, Lise Madsen, K Kristiansen, L Madsen
Journal of Lipid Research 44 p. 2320-2330
2001

Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status

Karl Johan Tronstad, Kjetil Berge, Endre Dyrøy, Lise Madsen, Rolf Kristian Berge
Biochemical Pharmacology 61 p. 639-649
2000

Peroxisome Proliferator-activated Receptor a Activators Improve Insulin Sensitivity and Reduce Adipoisty

Michèle Guerre-Millo, Phillippe Gervois, Eric Raspé, Lise Madsen, Philippe Poulain, Bruno Derudas, Jean-Marc Herbert, Deborah A. Winegar, Timothy M. Willson, Jean-Charles Fruchart, Rolf Kristian Berge, Bart Staels
Journal of Biological Chemistry 275 p. 16638-16642
2000

Proliferation of mitochondria and gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in rat skeletal muscle, heart and liver by hypolipidemic fatty acids

Geir Kåre Totland, Lise Madsen, Beate Klementsen, Hege Vaagenes, Harald Kryvi, Livar Frøyland, Sofie Hexeberg, Rolf Kristian Berge
Biology of the Cell p. 317-329
1999

Methylated eicosapentaenoic acid and tetradecylthioacetic acid: Effects on fatty acid metabolism

Hege Vaagenes, Lise Madsen, Endre Dyrøy, Morten Elholm, Agnete Stray-Pedersen, Livar Frøyland, Øyvind Lie, Rolf Kristian Berge
Biochemical Pharmacology 58 p. 1133-1143
1999

Beneficial Effects of Fibrates on Apolipoprotein A-I Metabolism Occur Independently of Any Peroxisome Proliferative Response

Nathalie Hennuyer, Philippe Poulain, Lise Madsen, Rolf Kristian Berge, Louis-Marie Houdebine, Didier Branellec, Jean-Charles Fruchart, Catherine Fiévet, Nicolas Duverger, Bart Staels
Circulation 99 p. 2445-2451
1999

In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacyllycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation

Rolf Kristian Berge, Lise Madsen, Hege Vaagenes, Karl Johan Tronstad, Martin Göttlicher, Arild C. Rustan
Biochemical Journal 343 p. 191-197
1999

Modulation of rat liver apolipoprotein gene expression and serum lipid levels by tetradecylthioacetic acid (TTA) via PPARa activation

E. Rasepé, Lise Madsen, M-M. Lefebvre, I. Leitersdorf, L. Gelman, J. Peinado-Onsurbe, J. Dallongeville, Jean-Charles Fruchart, Rolf Kristian Berge, B. Staels
Journal of Lipid Research 40 p. 2099-2110
1999

Metochondrial 3-Hydroxy-3-Methylglutaryl Coenzyme A Synthase and Carnitine Palmitoyltransferase II as Potential Control sites for Ketogenesis during Mitochondrion and Peroxisome Proliferation

Lise Madsen, Alexis Garras, Guilermina Asins, Dolors Serra, Fausto G. Hegardt, Rolf Kristian Berge
Biochemical Pharmacology 57 p. 1011-1019
1999

3-Thia Fatty Acid Treatment, in Contrast to Eicosapentaenoic Acid and Starvation, Induces Gene Expression of Carnitine Palmitoyltransferase-II in Rat Liver

Lise Madsen, Rolf Kristian Berge
Lipids 34 p. 447-456
1999

Eicosapentaenoic and docosahexaenoic Acid Affect Mitochondrial and Peroxisomal Fatty Acid Oxidation in Relation to Substrate Preference

Lise Madsen, Arild C. Rustan, Hege Vaagenes, Kjetil Berge, Endre Dyrøy, Rolf Kristian Berge
Lipids 34 p. 951-963
1999

Eicosapentaenoic and docosahexaenoic acid affect mitochondrial and peroxisomal fatty acid oxidation in relation to substrate preference

Lise Madsen, Arild C. Rustan, Hege Wergedahl, Kjetil Berge, Endre Dyrøy, Rolf Kristian Berge
Lipids 34 p. 951-963
1999

Methylated eicosapentaenoic acid and tetradecylthioacetic acid: effects on fatty acid metabolism

Hege Wergedahl, Lise Madsen, Endre Dyrøy, M Elholm, A Stray-Pedersen, Livar Frøyland, O Lie, Rolf Kristian Berge
Biochemical Pharmacology 58 p. 1133-1143
1998

Hypolipidemic n-3 fatty acids increases the antioxidant defence system to inhibit increased plasma and LDL lipid peroxidation

Hege Vaagenes, Ziad A. Muna, Lise Madsen, Rolf Kristian Berge
Lipids 33 p. 1131-1137
1998

Acute modulation of genes encoding peroxisomal and mitochondrial _b-oxidation enzymes by 3-thia fatty acids

Hege Vaagenes, Lise Madsen, D. Asiedu, Johan Lillehaug, Rolf Kristian Berge
Biochemical Pharmacology 56 p. 1571-1582
1998

Carnitine Palmitloyltransferase I, Carnitine Palmityltransferase II, and Acyl-CoA Oxidase Activities in Atlantic Salmon (Salmo slar)

Livar Frøyland, Lise Madsen, K. M. Echoff, Ø Lie, Rolf Kristian Berge
Lipids 33 p. 923-930
1998

Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation

Lise Madsen, Livar Frøyland, Endre Dyrøy, Kari Helland, Rolf Kristian Berge
Journal of Lipid Research 38 p. 583-593
1998

Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation

Lise Madsen, Livar Frøyland, Endre Dyrøy, Kari Helland, Rolf Kristian Berge
Journal of Lipid Research 39 p. 583-593
1997

Effect of 3-thia fatty acids on the lipid composition of rat liver, lipoproteins, and heart

Livar Frøyland, Lise Madsen, W. Sjursen, Alexis Garras, Ø. Lie, Jon Songstad, A. C. Rustan, Rolf Kristian Berge
Journal of Lipid Research 38 p. 1522-1534
1997

Up-regulated _D(9)-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: Accumulation of a _D(9)-desaturated metabolite of tetradecylthioacetic acid

Lise Madsen, Livar Frøyland, H.J Grav, Rolf Kristian Berge
Journal of Lipid Research 38 p. 554-563
1997

Mitochondrion is the principal target for nutritional and pharmacological control of triglyceride metabolism

Livar Frøyland, Lise Madsen, Hege Vaagenes, Geir Kåre Totland, J. Auwerx, Harald Kryvi, B Staels, Rolf Kristian Berge
Journal of Lipid Research 38 p. 183-190
1997

Mitochondrion is the principal target for nutitional and pharmacological control of triglyceride metabolism

Livar Frøyland, Lise Madsen, H Vaagenes, Geir Kåre Totland, J Auwerx, Harald Kryvi, B Staels, Rolf Kristian Berge
Journal of Lipid Research 38 p. 183-190
1994

Adsorption of Benzoic Acid on _a-Alumina and _g-Boehmite

Lise Madsen, Anne Marit Blokhus
Journal of Colloid and Interface Science 166 p. 259

Kapitler og bøker

2017

Chronic fast food intake promotes diet-induced obesity and cecal microbiota changes compared to a homemade healthy meal in C57BL/6J mice

Ida Rud, Jacob Bak Holm, Ingrid Måge, Charlotte Ramstad Kleiveland, Dimitrios Tzimorotas, Tor Erling Lea, Karsten Kristiansen, Lise Madsen, Bjørn Liaset

Rapporter og avhandlinger

1999

In favor of the mitochondria as the principal target for control of triacylglycerol metabolism. Modulation of hepatic fatty acid metabolism by poorly oxidizable faty acid

Madsen, Lise
1995

On the mechanism of the hypolipidemic effect of 3-THIA fatty acids with different chain length in rats. Fatty acid matabolizing enzymes and their mRNA levels. Hovedoppgave (cand.scient.)

Madsen, Lise
1995

On the mechanism of the hypolipedemic effect of 3-thia fatty acids with different chain length in rats. Fatty acid netabolizing enzymes and their m-rna levels

Madsen, Lise

Poster

2015

The role of fisheries and aquaculture in nutrition security

Livar Frøyland, Øyvind Lie, Marian Kjellevold Malde, Lise Madsen, Amund Måge, Bente Elisabeth Torstensen, Gro Ingunn Hemre, Ingvild Eide Graff
2014

The cardioprotective effect of the modern Atlantic salmon - dietary spillover from fish

Annette Bernhard, Josef Daniel Rasinger, LK Mitdbø, Lene Secher Myrmel, Bente Elisabeth Torstensen, K Kristiansen, Lise Madsen, Trond Brattelid
2013

alpha HBCD: Effect or no effect - A matter of diet?

Annette Bernhard, Lene Secher Myrmel, Lisa Kolden Mitbø, Mohammad Madani Ibrahim, Josef Daniel Rasinger, Bente Elisabeth Torstensen, Lise Madsen, Trond Brattelid
2012

Candidate genes for fat regain after weight cycling in mice

Simon E Nitter Dankel, Eirik Magnus Meek Degerud, Even Fjære, Christine Haugen, Jørn V. Sagen, Gunnar Mellgren, Lise Madsen
2012

CDKN1A associates with fat regain after weight cycling in mice

Eirik Magnus Meek Degerud, Simon E Nitter Dankel, Even Fjære, Christine Haugen, Jørn V. Sagen, Gunnar Mellgren, Lise Madsen

Jeg er forskningssjef i seksjon for Sjømat i modellsystem som pr i dag består av 13 forskere og stipendiater. Seksjonen har ansvar for overvåkning av miljøgifter og medisinrester i norsk oppdrettslaks. Vår forskning er i hovedsak fokusert på hvordan komponenter i sjømat, kan påvirke utvikling av fedme og diabetes. Vi arbeider både med forskjellige næringsstoffer og uønskede stoffer, som miljøgifter. I seksjonen bruker vi hovedsakelig mus og cellekulturer som modeller for å undersøke hvordan de forskjellige komponentene, både sammen og hver for seg, kan påvirke utviklingen av disse ikke-smittsomme sykdommene.



Prosjekter
Vitenskaplige publikasjoner


  • 2015


    Ole Jakob Nøstbakken, Helge Torbjørn Hove, Arne Duinker, Anne-Katrine L. Haldorsen, Marc Berntssen, Rita Hannisdal, Bjørn Tore Lunestad, Amund Måge, Lise Madsen, Bente Elisabeth Torstensen, Kåre Julshamn

    Contaminant levels in Norwegian farmed Atlantic salmon (Salmo salar) in the 13-year period from 1999 to 2011

    Environment International; Volum 74. S. 274-280
    • År: 2015

    Jacob Bak Holm, Daniel Sorobetea, Pia Kiilerich, Yuliaxis Ramayo-Caldas, Jordi Estellé, Tao Ma, Lise Madsen, Karsten Kristiansen, Marcus Svensson-Frej

    Chronic Trichuris muris infection decreases diversity of the intestinal microbiota and concomitantly increases the abundance of lactobacilli

    PLoS ONE; Volum 10.(5)
    • År: 2015

    Fredrik Bäckhed, Josefine Roswall, Yangqing Peng, Qiang Feng, Huijue Jia, Petia Kovatcheva-Datchary, Yin Li, Yan Xia, Hailiang Xie, Huanzi Zhong, Muhammad Tanweer Khan, Jianfeng Zhang, Junhua Li, Liang Xiao, Jumana Al-Aama, Dongya Zhang, Ying Shiuan Lee, Dorota Kotowska, Camilla Colding, Valentina Tremaroli, Ye Yin, Stefan Bergman, Xun Xu, Lise Madsen, Karsten Kristiansen, Jovanna Dahlgren, Wang Jun

    Dynamics and stabilization of the human gut microbiome during the first year of life

    Cell Host and Microbe; Volum 17.(5) S. 690-703
    • År: 2015

    Lisa Kolden Midtbø, Alison G. Borkowska, Annette Bernhard, Alexander Rønnevik, Erik-Jan Lock, Michael L. Fitzgerald, Bente Elisabeth Torstensen, Bjørn Liaset, Trond Brattelid, Theresa L. Pedersen, John W. Newman, Karsten Kristiansen, Lise Madsen

    Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice

    Journal of Nutritional Biochemistry; Volum 26.(6) S. 585-595
    • År: 2015

    Qin Hao, Rachita Yadav, Astrid L. Basse, Sidsel Petersen, Si B. Sonne, Simon Rasmussen, Qianhua Zhu, Zhike Lu, Jun Wang, Karine Audouze, Ramneek Gupta, Lise Madsen, Karsten Kristiansen, Jacob B. Hansen

    Transcriptome profiling of brown adipose tissue during cold exposure reveals extensive regulation of glucose metabolism

    American Journal of Physiology. Endocrinology and Metabolism; Volum 308.(5) S. E380-E392
    • År: 2015

    Morten Rahr Clausen, Xumin Zhang, Christian Clement Yde, Ditte Bruun Ditlev, Haldis Haukås Lillefosse, Lise Madsen, Karsten Kristiansen, Bjørn Liaset, Hanne Christine Bertram

    Intake of hydrolyzed casein is associated with reduced body fat accretion and enhanced phase II metabolism in obesity prone C57BL/6J mice

    PLoS ONE; Volum 10.(3)
    • År: 2015

    Liang Xiao, Qiang Feng, Suisha Liang, Si Brask Sonne, Zhongkui Xia, Xinmin Qiu, Xiaoping Li, Hua Long, Jianfeng Zhang, Dongya Zhang, Chuan Liu, Zhiwei Fang, Joyce Chou, Jacob Glanville, Qin Hao, Dorota Kotowska, Camilla Colding, Tine Rask Licht, Donghai Wu, Jun Yu, Joseph Jao Yiu Sung, Qiaoyi Liang, Junhua Li, Huijue Jia, Zhou Lan, Valentina Tremaroli, Piotr Dworzynski, H. Bjørn Nielsen, Fredrik Bäckhed, Joël Doré, Emmanuelle Le Chatelier, S. Dusko Ehrlich, John C. Lin, Manimozhiyan Arumugam, Jun Wang, Lise Madsen, Karsten Kristiansen

    A catalog of the mouse gut metagenome

    Nature Biotechnology; Volum 33.(10) S. 1103-1108
    • År: 2015

    Marianne U. Jakobsen, Lise Madsen, Claus Dethlefsen, Karen M. Due, Jytte Halkjær, Thorkild I.A. Sørensen, Karsten Kristiansen, Kim Overvad

    Dietary n-6 PUFA, carbohydrate:protein ratio and change in body weight and waist circumference: A follow-up study

    Public Health Nutrition; Volum 18.(7) S. 1317-1323
    • År: 2015

    Even Fjære, Charlotte Andersen, Lene Secher Myrmel, Rasmus Koefoed Petersen, Jakob Bondo Hansen, Hanne Sørup Tastesen, Thomas Mandrup-Poulsen, Nils Brünner, Karsten Kristiansen, Lise Madsen, Maria Unni Rømer

    Tissue inhibitor of matrix metalloproteinase-1 is required for high-fat diet-induced glucose intolerance and hepatic steatosis in mice

    PLoS ONE; Volum 10:e0132910.(7)
    • År: 2015
  • 2014


    Anita Røyneberg Alvheim, Bente Elisabeth Torstensen, Yu Hong Lin, Haldis Haukås Lillefosse, Erik-Jan Lock, Lise Madsen, Livar Frøyland, Joseph R. Hibbeln, Marian Kjellevold Malde

    Dietary linoleic acid elevates the endocannabinoids 2-AG and anandamide and promotes weight gain in mice fed a low fat diet

    Lipids; Volum 49.(1) S. 59-69
    • År: 2014

    Philip Hallenborg, Rasmus Koefoed Petersen, Søren Feddersen, Ulrik Sundekilde, Jacob B Hansen, Blagoy Blagoev, Lise Madsen, Karsten Kristiansen

    PPARγ ligand production is tightly linked to clonal expansion during initiation of adipocyte differentiation

    Journal of Lipid Research; Volum 55. S. 2491-2500
    • År: 2014

    Even Fjære, Ulrike Liisberg Aune, Kristin Røen, Alison H. Keenan, Tao Ma, Kamil Borkowski, David M. Kristensen, Guy W Novotny, Thomas Mandrup-Poulsen, Brian D. Hudson, Graeme Milligan, Yannan Xi, John W. Newman, Fawaz G. Haj, Bjørn Liaset, Karsten Kristiansen, Lise Madsen

    Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J mice

    Journal of Biological Chemistry; Volum 289.(23) S. 16032-16045
    • År: 2014

    Christian Clement Yde, Morten Rahr Clausen, Ditte Bruun Ditlev, Haldis Haukås Lillefosse, Lise Madsen, Karsten Kristiansen, Bjørn Liaset, Hanne Christine Bertram

    Multi-block PCA and multi-compartmental study of the metabolic responses to intake of hydrolysed versus intact casein in C57BL/6J mice by NMR-based metabolomics

    Metabolomics; S. 1-12
    • År: 2014

    Hanne Sørup Tastesen, Alison H. Keenan, Lise Madsen, Karsten Kristiansen, Bjørn Liaset

    Scallop protein with endogenous high taurine and glycine content prevents high-fat, high-sucrose-induced obesity and improves plasma lipid profile in male C57BL/6J mice

    Amino Acids; Volum 46.(7) S. 1659-1671
    • År: 2014

    Haldis Haukås Lillefosse, Morten Rahr Clausen, Christian Clement Yde, Ditte Bruun Ditlev, Xumin Zhang, Zhen-yu Du, Hanne Christine Bertram, Lise Madsen, Karsten Kristiansen, Bjørn Liaset

    Urinary loss of tricarboxylic acid cycle intermediates as revealed by metabolomics studies: An underlying mechanism to reduce lipid accretion by whey protein ingestion?

    Journal of Proteome Research; Volum 13.(5) S. 2560-2570
    • År: 2014

    Hanne Sørup Tastesen, Alexander Rønnevik, Kamil Borkowski, Lise Madsen, Karsten Kristiansen, Bjørn Liaset

    A mixture of cod and scallop protein reduces adiposity and improves glucose tolerance in high-fat fed male C57BL/6J mice

    PLoS ONE; Volum 9.(11)
    • År: 2014

    Simon E Nitter Dankel, Eirik Magnus Meek Degerud, Kamil Borkowski, Even Fjære, Lisa Kolden Midtbø, Christine Haugen, Margit Solsvik, Ann Marie Lavigne, Bjørn Liaset, Jørn V. Sagen, Karsten Kristiansen, Gunnar Mellgren, Lise Madsen

    Weight cycling promotes fat gain and altered clock gene expression in adipose tissue in C57BL/6J mice

    American Journal of Physiology. Endocrinology and Metabolism; Volum 306.(2) S. E210-E224
    • År: 2014

    Kamil Borkowski, Krzysztof Wrzesinski, Adelina Rogowska-Wrzesinska, Karine Audouze, Jesse Bakke, Rasmus Koefoed Petersen, Fawaz G. Haj, Lise Madsen, Karsten Kristiansen

    Proteomic analysis of cAMP-mediated signaling during differentiation of 3 T3-L1 preadipocytes

    Biochimica et Biophysica Acta - Proteins and Proteomics; Volum 1844.(12) S. 2096-2107
    • År: 2014
  • 2013


    Lisa Kolden Midtbø, Mohammad Madani Ibrahim, Lene Secher Myrmel, Ulrike Liisberg Aune, Anita Røyneberg Alvheim, Nina Sylvia Liland, Bente Elisabeth Torstensen, Grete Rosenlund, Bjørn Liaset, Trond Brattelid, Karsten Kristiansen, Lise Madsen

    Intake of farmed atlantic salmon fed soybean oil increases insulin resistance and hepatic lipid accumulation in mice

    PLoS ONE; Volum 8.(1)
    • År: 2013

    Zhen-yu Du, Tao Ma, Bjørn Liaset, Alison H. Keenan, Pedro Araujo, Erik-Jan Lock, Laurent Demizieux, Pascal Degrace, Livar Frøyland, Karsten Kristiansen, Lise Madsen

    Dietary eicosapentaenoic acid supplementation accentuates hepatic triglyceride accumulation in mice with impaired fatty acid oxidation capacity

    Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids; Volum 1831.(2) S. 291-299
    • År: 2013
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