Josef Rasinger

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Forsker
Telefon: 90362898
Avdeling: Trygt fôr

Jeg er ernæringstoksikolog som koordinerer og administrerer eksperimenter for mat- og fôrtrygghet. Min forskning er fokusert på analyse av interaksjoner mellom mat og fremmedstoff. Jeg er spesielt interessert i utvikling og implementering av molekylære (omics), biostatistiske og bioinformatiske verktøy til bruk i mat- og fôrsikkerhetsvurderinger.

Publikasjoner

Faglige foredrag

2016

Evaluation of the maximum limit for selenium in feed for salmonids

Robin Ørnsrud, Heidi Amlund, Pål Asgeir Olsvik, Josef Daniel Rasinger, T Sundal, Kristin Hamre, M Hillestad, Louise Buttle, Anne-Katrine L. Haldorsen, Marc Berntssen
2015

Disruption of calcium and zinc signalling in the murine brain following dietary exposure to TCDD, HBCD, BDE-47 and CB-153

Josef Daniel Rasinger, Thomas Samuel Carroll, Anne-Katrine L. Haldorsen, Christer Hogstrand
2015

Estudio de proteómica y bioinformática revela nuevas perspectivas en la neurotoxicidad del metilmercurio y la influencia del selenio en el cerebro del pez cebra (Danio rerio)

Josef Daniel Rasinger, Anne-Katrine L. Haldorsen, Ståle Ellingsen, Heidi Amlund
2015

An investigation of MeHg neurotoxicity and the influence of selenium in brain of zebrafish (Danio rerio) using proteomic tools

Heidi Amlund, Anne-Katrine L. Haldorsen, Ståle Ellingsen, Josef Daniel Rasinger
2014

Mining for species and tissue specific peptide biomarkers for the quantitative differentiation of processed animal protein in aquafeeds

Josef Daniel Rasinger, Marc Berntssen
2014

Peptidomics in Aquaculture – Developing peptide markers for the quantitative species and tissue specific differentiation of processed animal protein in aquafeeds

Josef Daniel Rasinger, Marc Berntssen
2014

Cross-omics assessment of the cytotoxicity of hexavalent chromium, Cr(VI), in primary Atlantic salmon hepatocytes

Josef Daniel Rasinger, Liv Ingeborg Rosvoll Søfteland, Pål Asgeir Olsvik
2014

On the use of molecular (omics) and bioinformatics tools in modern aquaculture

Rasinger, Josef Daniel
2013

Ontogeny of the redox balance in relation to organogenesis in Atlantic cod (Gadus morhua) larvae

Kristin Hamre, Samuel Penglase, Josef Daniel Rasinger, Kaja Helvik Skjærven, Pål Asgeir Olsvik
2013

Developing peptide biomarkers for the quantitative species and tissue specific differentiation of processed animal protein in aquafeeds

Josef Daniel Rasinger, Marc Berntssen
2012

How Nutrients modify the response to dietary contaminants. Invited speaker

Rasinger, Josef Daniel
2011

Interactions between nutrients and persistent organic pollutants in mice fed spiked fish-based or casein-based diets

Josef Daniel Rasinger, Thomas Samuel Carroll, Valentina Reffatto, Francesca Maranghi, Roberta Tassinari, Marte Haave, Anne-Katrine L. Haldorsen, Christer Hogstrand
2011

An Integrated approach to assess Toxicity of brominated flame Retardants in Mouse Models

Josef Daniel Rasinger, Thomas Samuel Carroll, Valentina Reffatto, Francesca Maranghi, Roberta Tassinari, Marte Haave, Alberto Mantovani, Anne-Katrine L. Haldorsen, Christer Hogstrand
2010

A transcriptomics approach to assess effects of four contaminants (2,3,7,8-TCDD, CB-153, BDE-47 and HBCD) commonly found in seafood

Thomas Samuel Carroll, Josef Daniel Rasinger, Valentina Reffatto, Roberta Tassinari, Ilaria Altieri, Francesca Maranghi, Gabriele Moracci, P Patriarca, Marte Haave, Alberto Mantovani, Antonio Menditto, A Marci, Anne-Katrine L. Haldorsen
2009

Proteomic assessment of the impact of dietary exposure to organic contaminants commonly found in farmed salmon (PCB-153, PBDE-47, HBCD, and TCDD-2378) on the neurodevelopment of juvenile Balb/c mice

Josef Daniel Rasinger, Thomas Samuel Carroll, VR Preedy, Christer Hogstrand
2009

DIGE Based Detection of Xenobiotic Induced Alterations in the Mouse Brain Proteome – Methodological Considerations

Rasinger, Josef Daniel
2008

Difference in Gel analysis of the murine brain proteome after exposure to PCB-153, PBDE-47, HBCD, and TCDD-2378

Josef Daniel Rasinger, Thomas Samuel Carroll, Valentina Reffatto, Marte Haave, Anne-Katrine L. Haldorsen, Christer Hogstrand
2007

Proteomic characterization of risks and benefits associated with consumption of farmed salmon

Josef Daniel Rasinger, Thomas Samuel Carroll, Christer Hogstrand

Vitenskapelige artikler (NVI)

2018

Transepithelial transfer of phenanthrene, but not of benzo[a]pyrene, is inhibited by fatty acids in the proximal intestine of rainbow trout (Oncorhynchus mykiss)

Stefan de Gelder, Henrik Sundh, Thamar NM Pelgrim, Josef Daniel Rasinger, Lotte van Daal, Gert Flik, Marc Berntssen, Peter H.M. Klaren
204 p. 97-105
2018

Dietary pesticide chlorpyrifos-methyl affects arachidonic acid metabolism including phospholipid remodeling in Atlantic salmon (Salmo salar L.)

Monica Sanden, Pål Asgeir Olsvik, Liv Ingeborg Rosvoll Søfteland, Josef Daniel Rasinger, Grethe Rosenlund, B Garlito, Maria Ibanez, Marc Berntssen
Aquaculture 484 p. 1-12
2018

Low dose exposure to HBCD, CB-153 or TCDD induces histopathological and hormonal effects and changes in brain protein and gene expression in juvenile female BALB/c mice

Josef Daniel Rasinger, Thomas Samuel Carroll, Francesca Maranghi, Roberta Tassinari, Gabriele Moracci, Ilaria Altieri, Alberto Mantovani, Anne-Katrine Lundebye, Christer Hogstrand
Reproductive Toxicology
2018

Factors influencing risk assessments of brominated flame-retardants; evidence based on seafood from the North East Atlantic Ocean

Ole Jakob Nøstbakken, Arne Duinker, Josef Daniel Rasinger, Bente Merete Nilsen, Monica Sanden, Sylvia Frantzen, Helge Torbjørn Hove, Anne-Katrine Lundebye, Marc Berntssen, Rita Hannisdal, Lise Madsen, Amund Måge
Environment International 119 p. 544-557
2018

Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice

Annette Bernhard, Josef Daniel Rasinger, Helene Wisløff, Øyvor Kolbjørnsen, Lene Secher Myrmel, Marc Berntssen, Anne-Katrine Lundebye, Robin Ørnsrud, Lise Madsen
Food and Chemical Toxicology 118 p. 608-625
2017

Lower levels of Persistent Organic Pollutants, metals and the marine omega 3-fatty acid DHA in farmed compared to wild Atlantic salmon (Salmo salar)

Anne-Katrine L. Haldorsen, Erik-Jan Lock, Josef Daiel Rasinger, Ole Jakob Nøstbakken, Rita Hannisdal, Egil Karlsbakk, Vidar Wennevik, Abdullah Sami Madhun, Lise Madsen, Ingvild Eide Graff, Robin Ørnsrud
Environmental Research 155 p. 49-59
2017

Vitamin E reduces endosulfan-induced toxic effects on morphology and behavior in early development of zebrafish (Danio rerio)

Karina Dale, Josef Daiel Rasinger, Kjetil Løtveit Thorstensen, Samuel Penglase, Ståle Ellingsen
Food and Chemical Toxicology 101 p. 84-93
2017

Methylmercury induced neurotoxicity and the influence of selenium in the brains of adult Zebrafish (Danio rerio)

Josef Daiel Rasinger, Anne-Katrine L. Haldorsen, Samuel Penglase, Ståle Ellingsen, Heidi Amlund
International Journal of Molecular Sciences 18:725 p. 1-14
2017

Sensitivity and toxic mode of action of dietary organic and inorganic selenium in Atlantic salmon (Salmo salar)

Marc Berntssen, Tone Kristin Sundal, Pål Asgeir Olsvik, Heidi Amlund, Josef Daiel Rasinger, Veronika Sele, Kristin Hamre, Marie Hillestad, Louise Buttle, Robin Ørnsrud
Aquatic Toxicology 192 p. 116-126
2017

In-depth metabolic profiling of marine macroalgae confirms strong biochemical differences between brown, red and green algae

Ikram Belghit, Josef Daiel Rasinger, Svenja Heesch, Irene Biancarosa, Nina Sylvia Liland, Bente Elisabeth Torstensen, Rune Waagbø, Erik-Jan Lock, Christian Guido Bruckner
Algal Research 26 p. 240-249
2017

Phosphoprotein DIGE profiles reflect blast differentiation, cytogenetic risk stratification, FLT3/NPM1 mutations and therapy response in acute myeloid leukaemia

Rakel Brendsdal Forthun, Elise Aasebø, Josef Daiel Rasinger, Siv Lise Bedringaas, Frode Berven, Frode Selheim, Øystein Bruserud, Bjørn Tore Gjertsen
Journal of Proteomics 173 p. 32-41
2017

Uptake of benzo[a]pyrene, but not of phenanthrene, is inhibited by fatty acids in intestinal brush border membrane vesicles of rainbow trout (Oncorhynchus mykiss)

Stefan de Gelder, Liselot van Och, Jan Zethof, Thamar NM Pelgrim, Josef Daiel Rasinger, Gert Flik, Marc Berntssen, Peter H.M. Klaren
195 p. 1-8
2017

Parallel in vivo and in vitro transcriptomics analysis reveals calcium and zinc signalling in the brain as sensitive targets of HBCD neurotoxicity

V Reffatto, Josef Daiel Rasinger, T.S. Carroll, T Ganay, Anne-Katrine Lundebye, I Sekler, M Hershfinkel, C Hogstrand
Archives of Toxicology 92 p. 1189-1203
2016

Vitamin A and arachidonic acid altered the skeletal mineralization in Atlantic cod (Gadus morhua) larvae without any interactions on the transcriptional level

Kai Kristoffer Lie, Karen Kvalheim, Josef Daniel Rasinger, Torstein Harboe, Andreas Hoel Nordgreen, Mari Moren
Comparative Biochemistry and Physiology A 191 p. 80-88
2016

Dietary vitamin A supplementation ameliorates the effects of poly-aromatic hydrocarbons in Atlantic salmon (Salmo salar)

Marc Berntssen, Robin Ørnsrud, Josef Daniel Rasinger, Liv Ingeborg Rosvoll Søfteland, Erik-Jan Lock, Kjersti Kolås, Mari Moren, Ketil Hylland, Joana Silva, Johan Johansen, Kai Kristoffer Lie
Aquatic Toxicology 175 p. 171-183
2016

The effect of dietary lipid composition on the intestinal uptake and tissue distribution of benzo[a]pyrene and phenanthrene in Atlantic salmon (Salmo salar)

Stefan de Gelder, Marit J. Bakke, Joelle Vos, Josef D. Rasinger, Kristian Ingebrigtsen, Merete Grung, Anders Ruus, Gert Flik, Peter H.M. Klaren, Marc H. G. Berntssen
185-186 p. 65-76
2016

Fish pre-acclimation temperature only modestly affects cadmium toxicity in Atlantic salmon hepatocytes

Pål Asgeir Olsvik, Liv Ingeborg Rosvoll Søfteland, Ernst Morten Hevrøy, Josef Daniel Rasinger, Rune Waagbø
Journal of Thermal Biology 57 p. 21-34
2016

Marine fatty acids aggravate hepatotoxicity of α-HBCD in juvenile female BALB/c mice

Annette Bernhard, Marc Berntssen, Anne-Katrine L. Haldorsen, Anita Røyneberg Alvheim, Lene Secher Myrmel, Even Fjære, Bente Elisabeth Torstensen, Karsten Kristiansen, Lise Madsen, Trond Brattelid, Josef Daniel Rasinger
Food and Chemical Toxicology 97 p. 411-423
2016

Species and tissues specific differentiation of processed animal proteins in aquafeeds using proteomics tools

Josef Daiel Rasinger, Helene Marbaix, Marc Dieu, Olivier Fumière, Sergio Mauro, Magnus Palmblad, Martine Raes, Marc Berntssen
Journal of Proteomics 16 p. 125-131
2015

Docosahexaenoic Acid Status in Pregnancy Determines the Maternal Docosahexaenoic Acid Status 3-, 6- and 12 Months Postpartum. Results from a Longitudinal Observational Study

Maria Wik, Josef Daniel Rasinger, Marian Kjellevold Malde, Livar Frøyland, Siv Skotheim, Hanne Cecilie Braarud, Kjell Morten Stormark, Ingvild Eide Graff
PLoS ONE 10
2014

Cross-omics gene and protein expression profiling in juvenile female mice highlights disruption of calcium and zinc signalling in the brain following dietary exposure to CB-153, BDE-47, HBCD or TCDD

Josef Daniel Rasinger, Thomas Samuel Carroll, Anne-Katrine L. Haldorsen, Christer Hogstrand
Toxicology 321 p. 1-12
2014

Selenium status affects selenoprotein expression, reproduction, and F1 generation locomotor activity in zebrafish (Danio rerio)

Samuel Penglase, Kristin Hamre, Josef Daniel Rasinger, Ståle Ellingsen
British Journal of Nutrition 111 p. 1918-1931
2014

Ontogeny of redox regulation in Atlantic cod (Gadus morhua) larvae

Kristin Hamre, Samuel Penglase, Josef Daniel Rasinger, Kaja Helvik Skjærven, Pål Asgeir Olsvik
73 p. 337-348
2013

Dietary exposure of juvenile female mice to polyhalogenated seafood contaminants (HBCD, BDE-47, PCB-153, TCDD): Comparative assessment of effects in potential target tissues

F. Maranghi, R. Tassinari, G. Moracci, I. Altieri, Josef Daniel Rasinger, T.S. Carroll, Christer Hogstrand, Anne-Katrine L. Haldorsen, A. Mantovani
Food and Chemical Toxicology 56 p. 443-449
2010

Systems biology investigation of the mechanisms of brominated flame retardant neurotoxicity

Christer Hogstrand, Thomas Samuel Carroll, Josef Daniel Rasinger, Valentina Reffatto, Anne-Katrine L. Haldorsen, Marte Haave, Roberta Tassinari, Ilaria Altieri, Francesca Maranghi, Gabriele Moracci, Marina Patriarca, Alberto Mantovani, Antonio Menditto, Agostino Macri
Comparative Biochemistry and Physiology A 157 p. S4-S4
2005

Evaluation of an FIA Operated Amperometric Bacterial Biosensor, Based on Pseudomonas Putida F1 for the Detection of Benzene, Toluene, Ethylbenzene, and Xylenes (BTEX)

Josef Daniel Rasinger, Giovanna Marrazza, Fabrizio Briganti, Andrea Scozzafava, Marco Mascini, Anthony P F Turner
Analytical Letters 38 p. 1531-1547

Annet tidsskriftbidrag

2009

Histopathological effects on target organ maturation in juvenile female mice upon exposure to 2,3,7,8-TCDD, PCB-153, PBDE-47 or HBCD through a salmon-based diet

Roberta Tassinari, Francesca Maranghi, Gabriele Moracci, Josef Daniel Rasinger, Thomas Samuel Carroll, Christer Hogstrand, Marte Haave, Anne-Katrine L. Haldorsen, Alberto Mantovani, Agostino Macri
Reproductive Toxicology 28 p. 127-127
2009

Histopathological effects of 2,3,7,8-TCDD, PCB-153, PBDE-47, and HBCD administered in a salmon-based diet to juvenile female balb/c mice

Francesca Maranghi, Gabriele Moracci, Roberta Tassinari, Josef Daniel Rasinger, Thomas Samuel Carroll, Christer Hogstrand, Marte Haave, Anne-Katrine L. Haldorsen, Alberto Mantovani, Agostino Macri
Experimental and Toxicological Pathology 61 p. 406-407
2009

Genomics-based assessment of toxicity in mice to four contaminants (2,3,7,8-TCDD, CB-153, BDE-47 AND HBCD), commonly found in seafood

Thomas Samuel Carroll, Josef Daniel Rasinger, Valentina Reffatto, Roberta Tassinari, Francesca Maranghi, Gabriele Moracci, Marte Haave, Alberto Mantovani, Agostino Macri, Anne-Katrine L. Haldorsen, Christer Hogstrand
Organohalogen Compounds 71

Rapporter og avhandlinger

2011

Proteomic Evaluation of the Neurotoxic Potential of Model Environmental Contaminants Commonly Found in Farmed Salmon

Rasinger, Josef Daniel

Poster

2016

Proteomics approaches for species and tissues specific differentiation of processed animal proteins in aquafeeds

Josef Daniel Rasinger, Helene Marbaix, Marc Dieu, Olivier Fumière, Sergio Mauro, Magnus Palmblad, Martine Raes, Marc Berntssen
2016

Transfer of mercury from feed to fish

Heidi Amlund, Anne-Katrine L. Haldorsen, Josef Daniel Rasinger, Marc Berntssen
2015

Cross-omic profiling reveals novel adverse outcome pathways in brains of juvenile female mice following dietary exposure to CB-153, BDE-47, HBCD or TCDD

Josef Daniel Rasinger, Thomas Samuel Carroll, Anne-Katrine L. Haldorsen, Christer Hogstrand
2015

Interaction of pesticides and antioxidant nutrients in zebrafish embryos.

Karina Dale, Kjetil Løtveit Thorstensen, Samuel Penglase, Josef Daniel Rasinger, Ståle Ellingsen
2015

Seafood consumption predicts the maternal docosahexaenoic acid status 3-, 6- and 12 months postpartum.

Maria Wik, Josef Daniel Rasinger, Marian Kjellevold Malde, Livar Frøyland, Siv Skotheim, Hanne Cecilie Braarud, Kjell Morten Stormark, Ingvild Eide Graff
2014

Environmental contaminants in mother and child - Is there a correlation between mothers seafood intake and levels of environmental persistent organic contaminants in mother and child at 3, 6 and 12 months post partum

Kaja Sørli, R. B. Barnung, Maria W. Markhus, Pedro Araujo, Josef Daniel Rasinger, Marian Kjellevold Malde, Anne-Katrine Lundebye, Robin Ørnsrud, Ingvild Eide Graff, Siv Skotheim, Hanne Cecilie Braarud, Kjell Morten Stormark, Trond Brattelid
2014

Bruk av LC-MS/MS for å karakterisere bioaktive peptider i Hpro®

Fiona Provan, Kjell Birger Øysæd, Marit Espe, Elisabeth Holen, Josef Daniel Rasinger, Eivind Larssen, Jørgen Seliussen
2014

The role of seafood intake in late pregnancy on mercury levels in hair of mothers and their infants

H.A.R Høgden, Annette Bernhard, Maria W. Markhus, Heidi Amlund, Anne-Katrine L. Haldorsen, Livar Frøyland, Lisbeth Dahl, Josef Daniel Rasinger, Ingvild Eide Graff, V Moe, L Smith, KM Stormark, Marian Kjellevold Malde, Trond Brattelid
2014

Interaction of pesticides and antioxidant nutrients in zebrafish embryos

K. Dale, KL Thorstensen, Samuel Penglase, Josef Daniel Rasinger, Ståle Ellingsen
2014

The cardioprotective effect of the modern Atlantic salmon - dietary spillover from fish

Annette Bernhard, Josef Daniel Rasinger, LK Mitdbø, Lene Secher Myrmel, Bente Elisabeth Torstensen, K Kristiansen, Lise Madsen, Trond Brattelid
2013

Dietary selenomethionine influences the toxicokinetics and –dynamics of dietary methylmercury in zebrafish (Danio rerio)

Heidi Amlund, Anne-Katrine L. Haldorsen, Josef Daniel Rasinger, David Boyle, Ståle Ellingsen
2013

alpha HBCD: Effect or no effect - A matter of diet?

Annette Bernhard, Lene Secher Myrmel, Lisa Kolden Mitbø, Mohammad Madani Ibrahim, Josef Daniel Rasinger, Bente Elisabeth Torstensen, Lise Madsen, Trond Brattelid
2012

Toxicoproteomics in zebrafish: Assessing the interaction between dietary selenium and methylmercury in brains of Danio rerio

Josef Daniel Rasinger, Anne-Katrine L. Haldorsen, Ståle Ellingsen, Heidi Amlund
2012

Evaluation of selenium modulated methylmercury neurotoxicity in zebrafish (Danio rerio) using proteomic tools

Josef Daniel Rasinger, Heidi Amlund, Anne-Katrine L. Haldorsen, Ståle Ellingsen
2012

Proteomic evaluation of the mechanisms involved in selenium modulated methylmercury neurotoxicity in zebrafish (Danio rerio)

Josef Daniel Rasinger, Ståle Ellingsen, Heidi Amlund, Anne-Katrine L. Haldorsen
2012

Assessment of protein expression profiles in livers of Atlantic salmon (Salmo salar) exposed to toxaphene-contaminated diets

Josef Daniel Rasinger, Erik-Jan Lock, Anne-Katrine L. Haldorsen
2012

An Integrated approach to assess Toxicity of brominated flame Retardants in Mouse Models

Øystein Sæle, Andreas Nordgreen, Josef Daniel Rasinger, Kristin Hamre
2010

Development of a proteomic workflow for neurotoxicity testing of dietary contaminants

Josef Daniel Rasinger, Thomas Samuel Carroll, Valentina Reffatto, Marte Haave, Anne-Katrine L. Haldorsen, Christer Hogstrand
2010

Proteomic Evaluation of the Effects of Model Dietary Contaminants on the Protein Expression Profiles of the Juvenile Murine Brain

Josef Daniel Rasinger, Thomas Samuel Carroll, Valentina Reffatto, Marte Haave, Anne-Katrine L. Haldorsen, Christer Hogstrand
Arbeidsområde
Utvalgte publikasjoner
Prosjekter
 

 

 

 

 

ernæring, toksikologi, proteomikk, biostatistikk, bioinformatikk, risikovurdering

Rasinger JD, Lundebye A-K, Penglase SJ, Ellingsen S, Amlund H. Methylmercury Induced Neurotoxicity and the Influence of Selenium in the Brains of Adult Zebrafish (Danio rerio). Int J Mol Sci. Multidisciplinary Digital Publishing Institute; 2017;18: 725.

Rasinger JD, Marbaix H, Dieu M, Fumière O, Mauro S, Palmblad M, et al. Species and tissues specific differentiation of processed animal proteins in aquafeeds using proteomics tools. J Proteomics. 2016;147: 125–131.

Cross-omics gene and protein expression profiling in juvenile female mice highlights disruption of calcium and zinc signalling in the brain following dietary exposure to CB-153, BDE-47, HBCD or TCDD. Rasinger, J. D., Carroll, T. S., Lundebye, A. K, Hogstrand. Toxicology, 321, 1-12. doi:10.1016/j.tox.2014.03.006

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