Anna Wargelius

Forskningssjef
Telefon: 90848168
Avdeling: Reproduksjon og utviklingsbiologi

Arbeidsområde

GROUP LEADER

Reproduction and Developmental Biology

RESEARCH INTERESTS

Gene expression pattern and level reflects to a significant extent the ongoing anatomical, morphological and physiological activities in a tissue and/or organism. My field of interest is functional genomics in Atlantic salmon with focus on the reproductive mechanisms. We currently use CRISPR-Cas9 to knockout (KO) genes in Atlantic salmon (Edvardsen et al 2014),  to be able to 1) explore molecular mechanisms related to the reproductive system, in particular germ cell specification and early sexual development, and we have recently produce germ cell free salmon by ablation of the primordial germ cells using CRISPR-Cas9 knockout of the dnd gene (PGCs, (Wargelius et al 2016). Both aims explore fields which can result in sterility models for aquaculture that could solve major bottlenecks related to un-wanted sexual maturation and genetic interactions with wild populations. Currently two of my projects are intensively exploring these fields, SALMOSTERILE 2013-2018 (NFR BIOTEK 2021 project, https://www.hi.no/salmosterile/nb-no ) and POSTSMOLTMAR (HAVBRUK 2 2016-2020).

We have also in recent years explored the wild genome pool of Atlantic salmon with the main aim to identify genetic regions under selection for primarily reproductive traits, such as time at maturity (Ayllon et al 2015) However studies have also revealed genetic regions /sweeps that probably confer traits associated with disease resistance, behaviour, sea water adaption and feed metabolism (Kjærner-Semb et al 2016). SALMAT 2013-2017 (NFR-BIOTEK 2021-HAVBRUK project), MATGEN 2016-2020 (NFR _HAVBRUK) and DIGISAL (Biotek2021-digital life project).

STUDENTs

(Current)

Erik Kjærner-Semb. GWAS to find trais under selection

(Past)
Shou Wang Current cosupervisor for PhD candidate in NFR FRIBIO project ” Deciphering embryonic segmentation, Genes that control the repeat pattern of the vertebral column.” 2011-2014 Thesis delivered Dec 18th 20

Lene Kleppe Current supervisor for PhD candidate in the EU project “LIFECYCLE”, (http://www.lifecycle-fp7.eu/). 2010-2013

Christel Krossøy Cosupervisor for PhD thesis, “Vitamin K in farmed Atlantic salmon (Salmo Salar L.) with emphasis on bone.”, dissertation for the degree philosophiae doctor (PhD), University of Bergen, Norway

Curriculum Vitae

Anna Sofie Troedsson-Wargelius (MSc, PhD)
Group leader, Principal Scientist (1183), Institute of Marine Research

DOB , 05.12.1972
Civil status Married, three children (6, 10 and 13 years)

FORMAL EDUCATION :
1998-2001 PhD Institute of Molecular Biology, University of Bergen, Norway
1991-1996 Master in Biology, University of Uppsala, Sweden

Publikasjoner

Vitenskapelige artikler (NVI)

2017

Integrative testis transcriptome analysis reveals differentially expressed miRNAs and their mRNA targets during early puberty in Atlantic salmon

Kai Ove Skaftnesmo, Rolf Edvardsen, Tomasz Furmanek, D. Crespo, Eva Andersson, Lene Kleppe, Geir Lasse Taranger, Jan Bogerd, Rüdiger W. Schulz, Anna Wargelius
BMC Genomics 18
2017

Sex steroid production associated with puberty is absent in germ cellfree salmon

Lene Kleppe, Eva Andersson, Kai Ove Skaftnesmo, Rolf Edvardsen, Per Gunnar Fjelldal, Birgitta Norberg, Jan Bogerd, Rüdiger W. Schulz, Anna Wargelius
Scientific Reports 7
2017

Rapid growth causes abnormal vaterite formation in farmed fish otoliths

Tormey Reimer, Timothy David Dempster, Anna Wargelius, Per Gunnar Fjelldal, Tom Johnny Hansen, Kevin Glover, Monica Favnebøe Solberg, Stephen E. Swearer
Journal of Experimental Biology 220 p. 2965-2969
2017

Susceptibility, behaviour, and retention of the parasitic salmon louse (Lepeophtheirus salmonis) differ with Atlantic salmon population origin

Samantha Bui, Sussie Dalvin, Timothy David Dempster, Ole Fredrik Skulstad, Rolf Edvardsen, Anna Wargelius, Frode Oppedal
Journal of Fish Diseases
2017

Functional Annotation of All Salmonid Genomes (FAASG): an international initiative supporting future salmonid research, conservation and aquaculture

Daniel J. Macqueen, Craig R. Primmer, Ross D. Houston, Barbara F. Nowak, Louis Bernatchez, Steinar Bergseth, William S. Davidson, Cristian Gallardo-Escárate, Tom Goldammer, Yann Guiguen, Patricia Iturra, James W. Kijas, Ben F. Koop, Sigbjørn Lien, Alejandro Maass, Samuel A. M. Martin, Philip McGinnity, Martin Montecino, Kerry Naish, Krista M. Nichols, Kristinn Ólafsson, Stig William Omholt, Yniv Palti, Graham S. Plastow, Caird E. 3rd Rexroad, Matthew L. Rise, Rachael J. Ritchie, Simen Rød Sandve, Patricia M. Schulte, Alfredo Tello, Rodrigo Vidal, Jon Olav Vik, Anna Wargelius, José Manuel Yáñez
BMC Genomics 18
2017

bmp15l, figla, smc1bl, and larp6l are preferentially expressed in germ cells in Atlantic salmon (Salmo salar L.)

Lene Kleppe, Rolf Edvardsen, Tomasz Furmanek, Eva Andersson, Amélie Juanchich, Anna Wargelius
Molecular Reproduction and Development 84 p. 76-87
2016

Dnd knockout ablates germ cells and demonstrates germ cell independent sex differentiation in Atlantic salmon

Anna Wargelius, Sven Dirk Leininger, Kai Ove Skaftnesmo, Lene Kleppe, Eva Andersson, Geir Lasse Taranger, Rüdiger W. Schulz, Rolf Edvardsen
Scientific Reports 6
2016

Atlantic salmon populations reveal adaptive divergence of immune related genes - A duplicated genome under selection

Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Tomasz Furmanek, Vidar Wennevik, Geir Dahle, Eero Niemelä, Mikhail Ozerov, Juha-Pekka Vähä, Kevin Glover, Carl J. Rubin, Anna Wargelius, Rolf Edvardsen
BMC Genomics 17:610 p. 1-12
2016

Increased dietary phosphorous prevents vertebral deformities in triploid Atlantic salmon (Salmo salar L.)

Per Gunnar Fjelldal, Tom Johnny Hansen, Erik-Jan Lock, Anna Wargelius, Thomas Fraser, Florian Sambraus, A. El-Mowafi, Sissel Albrektsen, Rune Waagbø, Robin Ørnsrud
Aquaculture Nutrition 22 p. 72-90
2016

Approaches for delaying sexual maturation in salmon and their possible ecological and ethical implications

Marianne Iversen, Anne Ingeborg Myhr, Anna Wargelius
Journal of Applied Aquaculture 28 p. 330-369
2015

The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon(Salmo salar L.) Males

Fernando Ayllon, Erik Nordtorp Kjærner-Semb, Tomasz Furmanek, Vidar Wennevik, Monica Favnebøe Solberg, Geir Dahle, Geir Lasse Taranger, Kevin Glover, Markus Sällman Almén, Carl J. Rubin, Rolf Edvardsen, Anna Wargelius
PLoS Genetics 11:e1005628
2015

A comparison between egg trancriptomes of cod and salmon reveals species-specific traits in eggs for each species

Anna Wargelius, Tomasz Furmanek, Jérôme Montfort, Aurélie Le Cam, Lene Kleppe, Amélie Juanchich, Rolf Edvardsen, Geir Lasse Taranger, Julien Bobe
Molecular Reproduction and Development 82 p. 397-404
2015

Gonad specific genes in Atlantic salmon (Salmon salar L.): Characterization of tdrd7-2, dazl-2, piwil1 and tdrd1 genes

Lene Kleppe, Anna Wargelius, Hanne Johnsen, Eva Andersson, Rolf Edvardsen
Gene 560 p. 217-225
2014

Global transcriptome analysis identifies regulated transcripts and pathways activated during oogenesis and early embryogenesis in atlantic cod

Lene Kleppe, Rolf Edvardsen, Tomasz Furmanek, Geir Lasse Taranger, Anna Wargelius
Molecular Reproduction and Development 81 p. 619-635
2014

Targeted mutagenesis in Atlantic salmon(Salmo salar L.)Using the CRISPR/Cas9 system induces Complete knockout individuals in the F0 generation

Rolf Edvardsen, Sven Dirk Leininger, Lene Kleppe, Kai Ove Skaftnesmo, Anna Wargelius
PLoS ONE 9 p. 1-7
2014

Transcriptome sequencing of Atlantic salmon (Salmo salar L.) notochord prior to development of the vertebrae provides clues to regulation of positional fate, chordoblast lineage and mineralisation

Shou Wang, Tomasz Furmanek, Harald Kryvi, Christel Krossøy, Geir Kåre Totland, Sindre Grotmol, Anna Wargelius
BMC Genomics 15:141
2013

Mineralization of the vertebral bodies in Atlantic salmon (Salmo salar L.) is initiated segmentally in the form of hydroxyapatite crystal accretions in the notochord sheath

Shou Wang, Harald Kryvi, Sindre Grotmol, Anna Wargelius, Christel Krossøy, Matthias Epple, Frank Neues, Tomasz Furmanek, Geir Kåre Totland
Journal of Anatomy 223 p. 159-170
2013

Cortisol treatment of prespawning female cod affects cytogenesis related factors in eggs and embryos

Lene Kleppe, Ørjan Karlsen, Rolf Edvardsen, Birgitta Norberg, Eva Andersson, Geir Lasse Taranger, Anna Wargelius
General and Comparative Endocrinology 189 p. 84-95
2012

Maternal 3 ' UTRs: from egg to onset of zygotic transcription in Atlantic cod

Lene Kleppe, Rolf Edvardsen, H Kuhl, Ketil Malde, Tomasz Furmanek, O Drivenes, R Reinhardt, Geir Lasse Taranger, Anna Wargelius
BMC Genomics 13
2012

Dietary phosphorus does not reduce the risk for spinal deformities in a model of adjuvant-induced inflammation in Atlantic salmon (Salmo salar) postsmolts

Laura Gil Martens, Per Gunnar Fjelldal, Erik-Jan Lock, Anna Sofie Troedsson Wargelius, Heidrun Inger Wergeland, P. Eckhard Witten, Tom Johnny Hansen, Rune Waagbø, Robin Ørnsrud
Aquaculture Nutrition 18 p. 12-20
2012

Stress and expression of cyclooxygenases (cox1, cox2a, cox2b) and intestinal eicosanoids, in Atlantic salmon

Rolf Erik Olsen, Asbjørn M. Svardal, Torunn Eide, Anna Wargelius
Fish Physiology & Biochemistry 38 p. 951-962
2012

Continuous light induces bone resorption and affects vertebral morphology in Atlantic salmon (Salmo salar L.) fed a phosphorous deficient diet

Per Gunnar Fjelldal, Erik-Jan Lock, Tom Johnny Hansen, Rune Waagbø, Anna Wargelius, Laura Gil Martens, Adel El-Mowafi, Robin Ørnsrud
Aquaculture Nutrition 18 p. 610-619
2012

Vertebral deformities in farmed Atlantic salmon (Salmo salar L.) - etiology and pathology

Per Gunnar Fjelldal, Tom Johnny Hansen, Olav Breck, Robin Ørnsrud, Erik-Jan Lock, Rune Waagbø, Anna Wargelius, Paul Eckhard Witten
Journal of Applied Ichthyology 28 p. 433-440
2011

Sustained swimming increases the mineral content and osteocyte density of salmon vertebral bone

Geir Kåre Totland, Per Gunnar Fjelldal, Harald Kryvi, Guro Løkka, Anna Sofie Troedsson Wargelius, Anita Sagstad, Tom Johnny Hansen, Sindre Grotmol
Journal of Anatomy 219 p. 490-501
2011

The effect of water temperature on vertebral deformities and vaccine-induced abdominal lesions in Atlantic salmon, Salmo salar L

Ane Grini, Tom Johnny Hansen, Arne Berg, Anna Wargelius, Per Gunnar Fjelldal
Journal of Fish Diseases 34 p. 531-546
2011

Identification of vimentin- and elastin-like transcripts specifically expressed in developing notochord of Atlantic salmon (Salmo salar L.)

Anita Sagstad, Sindre Grotmol, Harald Kryvi, Christel Krossøy, Geir Kåre Totland, Ketil Malde, Shou Wang, Tom Johnny Hansen, Anna Sofie Troedsson Wargelius
Cell and Tissue Research 346 p. 191-202
2010

Effects of vegetable feed ingredients on bone health in Atlantic salmon

Per Gunnar Fjelldal, Ulla Nordgarden, Anna Wargelius, Geir Lasse Taranger, Rune Waagbø, Rolf Erik Olsen
Journal of Applied Ichthyology 26 p. 327-333
2010

Dietary fatty acids and inflammation in the vertebral column of Atlantic salmon, Salmo salar L., smolts: a possible link to spinal deformities

Laura Gil Martens, ERIK-JAN LOCK, Per Gunnar Fjelldal, Anna Wargelius, HERNANDEZ PEDRO W ARAUJO, BENTE ELISABETH TORSTENSEN, P. Eckhard Witten, Tom Hansen, Rune Waagbø, ROBIN ØRNSRUD
Journal of Fish Diseases 33 p. 957-972
2010

MMP-13 (Matrix MetalloProteinase 13) expression might be an indicator for increased ECM remodeling and early signs of vertebral compression in farmed Atlantic salmon (Salmo salar L.)

Anna Wargelius, Per Gunnar Fjelldal, Ane Grini, Laura Gil-Martens, Bjørn Olav Kvamme, Tom Hansen
Journal of Applied Ichthyology 26 p. 366-371
2010

Collagen type XI alpha 1 may be involved in the structural plasticity of the vertebral column in Atlantic salmon (Salmo salar L.)

Anna Wargelius, Per Gunnar Fjelldal, Ulla Nordgarden, Ane Grini, Christel Krossøy, Sindre Grotmol, Geir Kåre Totland, Tom Hansen
Journal of Experimental Biology 213 p. 1207-1216
2009

Continuous light affects mineralization and delays osteoid incorporation in vertebral bone of Atlantic salmon (Salmo Salar L.)

Anna Wargelius, Per Gunnar Fjelldal, Ulla Nordgarden, Tom Johnny Hansen
Journal of Experimental Biology 212 p. 656-661
2009

Differential gene expression of bgp and mgp in trabecular and compact bone of Atlantic salmon (Salmo salar L.) vertebrae

Christel Krossøy, Robin Ørnsrud, Anna Wargelius
Journal of Anatomy 215 p. 663-672
2009

Dietary menadione nicotinamide bisulphite (vitamin K-3) does not affect growth or bone health in first-feeding fry of Atlantic salmon (Salmo salar L.)

Christel Krossøy, Rune Waagbø, Per Gunnar Fjelldal, Anna Wargelius, ERIK-JAN LOCK, Ingvild Eide Graff, ROBIN ØRNSRUD
Aquaculture Nutrition 15 p. 638-649
2007

Molecular mechanisms of contiuous light inhibition of Atlantic salmon parr-smolt transformation

Sigurd Stefansson, Tom Ole Nilsen, Lars Ebbesson, Anna Wargelius, Steffen S. Madsen, Bjørn Th. Bjørnsson, Stephen D. McCormich
Aquaculture 273 p. 235-245
2007

Molecular mechanisms of continuous light inhibition of Atlantic salmon parr-smolt transformation

Sigurd Stefansson, Tom Ole Nilsen, Lars Ebbesson, Anna Wargelius, Steffen S. Madsen, Björn Thrandur Björnsson, Stephen D. McCormick
Aquaculture 273 p. 235-245
2006

Growth hormone and insulin-like growth factor-I act together and independently when regulating growth in vertebral and muscle tissue of Atlantic salmon postsmolts

Ulla Nordgarden, Per Gunnar Fjelldal, Tom Johnny Hansen, Bjørn Thrandur Bjørnsson, Anna Wargelius
General and Comparative Endocrinology 149 p. 253-260
2006

Insight into the complex genetic network of tetraploid Atlantic salmon (Salmo salar L.): Description of multiple novel Pax7 splice variants

Susan Gotensparre, Eva Andersson, Anna Wargelius, Tom Johnny Hansen, Ian A. Johnston
Gene 373 p. 8-15
2005

A peak in gh-receptor expression is associated with growth activation in Atlantic salmon vertebrae, while upregulation of igf-I receptor expression is related to increased bone density

Anna Wargelius, Per Gunnar Fjelldal, Tom Johnny Hansen, Bjørn Thrandur Bjørnsson, Ulla Nordgarden, Susana Benedet
General and Comparative Endocrinology 142 p. 163-168
2005

Heat shock during early somitogenesis induces caudal vertebral column defects in Atlantic salmon (Salmo salar)

Anna Wargelius, Per Gunnar Fjelldal, Tom Johnny Hansen
Development, Genes and Evolution 215 p. 350-357
2005

Vertebrae of the trunk and tail display different growth rates in response to photoperiod in Atlantic salmon, Salmo salar L., post-smolts

Per Gunnar Fjelldal, Ulla Nordgarden, Arne Erik Berg, Anna Wargelius, Sindre Grotmol, Geir Kåre Totland, Tom Johnny Hansen
Aquaculture 250 p. 516-524
2004

Influence of egg vitamin A status and egg incubation temperature on subsequent development of the early vertebral column in Atlantic salmon (Salmo salar L.) fry

Robin Ørnsrud, Anna Wargelius, Øystein Sæle, Karin Pittman, Rune Waagbø
Journal of Fish Biology 64 p. 399-417
2004

Spring growth in the vertebrae of Atlantic salmon (Salmo salar) is characterized by a gradual increase in ihh expression, while a certain photoperiod triggers shh induction

Tom Johnny Hansen, Arne Erik Berg, Per Gunnar Fjelldal, Anna Wargelius, Ulla Nordgarden
Journal of Bone and Mineral Research 19 p. 217
2004

Influence of egg vitamin A status and egg incubation temperature on subsequent development of the early vertebral column in Atlantic salmon fry

R Ornsrud, A Wargelius, O Saele, Karin Pittman, R Waagbo
Journal of Fish Biology 64 p. 399-417
2003

Retinal expression of zebrafish six3.1 and its regulation by Pax6

Anna Wargelius, Hee-Chan Seo, Lars Austbø, Anders Fjose
Biochemical and Biophysical Research Communications - BBRC 309 p. 475-481
2001

RNA interference: mechanisms and applications

Anders Fjose, Ståle Ellingsen, Anna Wargelius, Hee-Chan Seo
Biotechnology Annual Review 7 p. 31-57
2000

Fas and Fas ligand gene polymorphisms in primary Sjögren's syndrome

Anne Isine Bolstad, Anna Wargelius, Britt Nakken, Hans-Jacob Haga, Roland Jonsson
Journal of Rheumatology 27 p. 2397-2405
2000

Fas and Fas ligand gene polymorphisms in primary Sjögren's syndrome

Anne Isine Bolstad, Anna Wargelius, Britt Makken, H.-J. Haga, Roland Jonsson
Journal of Rheumatology 27 p. 2397-2405
1999

Double-stranded RNA induces specific developmental defects in Zebrafish Embryos

A Wargelius, Ståle Ellingsen, Anders Fjose
Biochemical and Biophysical Research Communications - BBRC 263 p. 156-161
1999

Double-Stranded RNA Induces Specific Developmental Defects in Zebrafish Embryos

Anna Wargelius, Ståle Ellingsen, Anders Fjose
Biochemical and Biophysical Research Communications - BBRC 263 p. 156-161

Poster

2017

Triploid salmon - susceptibility to infectious viral diseases

Hilde Sindre, Torunn Taksdal, Anne Berit Olsen, Hanne Nilsen, Torkjel Bruheim, Anna Wargelius
2016

Differences among Atlantic salmon biologies in their susceptibility and behavioural response to infective sealice, Leperophtheirus salmonis, and the retention of lice.

Samantha Bui, Sussie Dalvin, Timothy David Dempster, Ole Fredrik Skulstad, Anna Wargelius, Frode Oppedal
2015

SCREENING FOR STERILITY CANDIDATE GENES IN ATLANTIC SALMON (SALMO SALAR)

Lene Kleppe, Rolf Edvardsen, Tomasz Furmanek, Eva Andersson, Anna Wargelius
2014

Candidate genes for sterility in Atlantic salmon (Salmo salar)

Lene Kleppe, Anna Wargelius, Eva Andersson, Geir Lasse Taranger, Rolf Edvardsen
2014

SMALL RNAS IN IMMATURE AND MATURE TESTIS OF ATLANTIC SALMON (SALMO SALAR L.)

Kai Ove Skaftnesmo, Rolf Edvardsen, Tomasz Furmanek, Eva Andersson, Lene Kleppe, Jan Bogerd, Rüdiger W. Schulz, Geir Lasse Taranger, Anna Wargelius
2013

Radiological studies on vertebral deformities in triploid Atlantic salmon (Salmo salar)

Thomas WK Fraser, Tom Johnny Hansen, M. Fleming, Florian Sambraus, Ian Mayer, Jon Egil Skjæraasen, Anna Wargelius, Robin Ørnsrud, Erik-Jan Lock, Per Gunnar Fjelldal
2011

The link between broodstock stress and offspring developmental potential in Atlantic cod Gadus morhua L

Lene Kleppe, Ørjan Karlsen, Rolf Edvardsen, Øyvind Drivenes, Birgitta Norberg, Geir Lasse Taranger, Anna Wargelius
2008

Inflammation as a risk factor for spinal deformities in farmed Atlantic salmon underyearling smolts

Laura Gil Martens, Erik-Jan Lock, Robin Ørnsrud, Per Gunnar Fjelldal, Anna Wargelius, Bente Elisabeth Torstensen, Paul Eckhard Witten, Tom Johnny Hansen, Rune Waagbø
2008

Dietary menadione nicotinamide bisulphite (vitamin K) does not affect growth or bone health in first feeding Atlantic salmon (Salmo salar)

Christel Krossøy, Rune Waagbø, Per Gunnar Fjelldal, Anna Wargelius, Erik-Jan Lock, Ingvild Eide Graff, Robin Ørnsrud
2007

Investigations on first feeding fry of Atlantic salmon (Salmo salar L.) fed diets with different levels of menadione nicotinamide bisulphite (MNB)

Christel Krossøy, Per Gunnar Fjelldal, Rune Waagbø, Anna Wargelius, Robin Ørnsrud
2007

Nutritional status of Atlantic salmon (Salmo salar) broodstock- A preliminary study on the maternal effects on early expression of leptin, IGF-I, IGF-IR, GH and GHR

Anne-Grethe Gamst Moen, Sigurd Stefansson, Ann-Elise Olderbakk Jordal, Tom Ole Nilsen, A Wargelius, Tadahide Kurokawa, Björn Thrandur Björnsson, Ivar Rønnestad
1998

A retroviral vector (MSCV) injected at distinct stages of development in zebrafish embryos

Ståle Ellingsen, Øyvind Drivenes, Anna Wargelius, Jan Harald Kristiansen, Ove Bruland, Johan Lillehaug, Anders Fjose

Populærvitenskapelige artikler

2016

Verdens første laks uten kjønnseller

Anna Wargelius, Rolf Edvardsen
Aftenposten Viten
2013

Utvikling av steril fisk ved hjelp av nye vaksinasjonsmetoder

Anna Wargelius, Rolf Edvardsen, Geir Lasse Taranger
Havbruk

Faglige foredrag

2018

Optimization of CRISPR/Cas9 knock-in technology and application in salmon

Rolf Edvardsen, Anne Hege Straume, Kai Ove Skaftnesmo, Lene Kleppe, hilal guralp, Anna Wargelius
2017

Gene editing a possible way to solve major sustainability issues in Atlantic salmon farming?

Wargelius, Anna
2017

Gene editing - adressing major sustainability issues in Atlantic salmon farming

Wargelius, Anna
2017

Gene editing. A game changer for aquaculture.

Wargelius, Anna
2017

The search for sustainable solution for coexistence but not mixing of farmed and wild salmon strains: Gene-editing to the rescue?

Dorothy Jane Dankel, Anna Wargelius
2016

Targeting germ cell survival factors to produce sterile salmon

Lene Kleppe, Anna Wargelius, Helge Tveiten, Sven Dirk Leininger, Kai Ove Skaftnesmo, Tomasz Furmanek, Rüdiger W. Schulz, Geir Lasse Taranger, Eva Andersson, Rolf Edvardsen
2016

Targeting germ cell survival factors to produce sterile salmon through vaccination

Lene Kleppe, Anna Wargelius, Helge Tveiten, Sven Dirk Leininger, Kai Ove Skaftnesmo, Tomasz Furmanek, Rüdiger W. Schulz, Geir Lasse Taranger, Eva Andersson, Rolf Edvardsen
2016

Sterile salmon by targeting factors involved in germ cell survival: novel strategies for sustainable fish farming

Lene Kleppe, Rolf Edvardsen, Helge Tveiten, Sven Dirk Leininger, Kai Ove Skaftnesmo, Eva Andersson, Geir Lasse Taranger, Rüdiger W. Schulz, Tomasz Furmanek, Anna Wargelius
2016

Functional studies in Atlantic salmon (Salmo salar L) reveals candidates for sterility vaccines.

Wargelius, Anna
2016

Targeted mutagenesis in Atlantic salmon using the CRISPR/Cas9 system

Rolf Edvardsen, Lene Kleppe, Kai Ove Skaftnesmo, Sven Dirk Leininger, Tomasz Furmanek, Geir Lasse Taranger, Rüdiger W. Schulz, Eva Andersson, Anna Wargelius
2016

Bruk av CRISPR/Cas9 i laks

Rolf Edvardsen, Lene Kleppe, Kai Ove Skaftnesmo, Sven Dirk Leininger, Tomasz Furmanek, Geir Lasse Taranger, Rüdiger W. Schulz, Eva Andersson, Anna Wargelius
2016

Genome resequencing of geographically distinct Atlantic Salmon (Salmo salar) populations reveals adaptive divergence

Rolf Edvardsen, Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Tomasz Furmanek, Vidar Wennevik, Geir Dahle, Eero Niemelä, Mikhail Ozerov, Juha-Pekka Vähä, Kevin Glover, Carl Johan Rubin, Anna Wargelius
2016

Adaptive plasticity in Atlantic salmon- genetic predisposition of time at maturity and environmental triggers

Rolf Edvardsen, Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Tomasz Furmanek, Tom Johnny Hansen, Per Gunnar Fjelldal, Carl Johan Rubin, Lene Kleppe, Kai Ove Skaftnesmo, Elin Sørhus, Faezeh Mohammadi, Geir Dahle, Vidar Wennevik, Monica Favnebøe Solberg, Kevin Glover, Birgitta Norberg, Geir Lasse Taranger, Eva Andersson, Rüdiger W. Schulz, Anna Wargelius
2015

Identification of novel sterility vaccine candidates, in RNAseq samples of Atlantic salmon testis.

Wargelius, Anna
2015

Reproductive constraints in salmon aquaculture using genomics

Wargelius, Anna
2014

A comparison between egg trancriptomes of cod and salmon reveals species specific traits in eggs for each species

Anna Wargelius, Tomasz Furmanek, Jerome Montfort, Aurelie Le Cam, Lene Kleppe, Rolf Edvardsen, Geir Lasse Taranger, Julien Bobe
2014

APPLICATIONS OF GENOME-WIDE TECHNIQUES TO STUDY SALMON PHYSIOLOGY, DEVELOPMENT AND REPRODUCTION

Geir Lasse Taranger, Rolf Edvardsen, Lene Kleppe, Eva Andersson, Anna Wargelius
2013

GLOBAL TRANSCRIPTOME ANALYSIS IDENTIFIES REGULATED TRANSCRIPTS AND PATHWAYS ACTIVATED DURING OOGENESIS AND EARLY EMBRYOGENESIS IN ATLANTIC COD

Lene Kleppe, Rolf Edvardsen, Tomasz Furmanek, Geir Lasse Taranger, Anna Wargelius
2013

DEEP SEQUENCING REVEALS MINERALIZING NOTOCHORD TRANSCRIPTOME, DURING AXIAL SKELETON ENFORCEMENT FROM NOTOCHORD TO VERTEBRA IN ATLANTIC SALMON (SALMO SALAR L.)

Shou Wang, Tomasz Furmanek, Harald Kryvi, Christel Krossøy, Geir Kåre Totland, Sindre Grotmol, Anna Wargelius
2013

GLOBAL AND LOCAL METHYLATION PATTERN IN TRIPLOID AND DIPLOID AND TRIPLOID ATLANTIC SALMON

Anna Wargelius, Tomasz Furmanek, Rolf Edvardsen, Elin Sørhus, Per Gunnar Fjelldal, Tom Johnny Hansen
2012

Attempts to induce sterility in Atlantic salmon by morfolino and zink finger techniques

Anna Wargelius, Rolf Edvardsen, Trine Haugen, Ståle Ellingsen, Eva Andersson, Ketil Malde, Ørjan Karlsen, Per Gunnar Fjelldal, Geir Lasse Taranger, Øyvind Drivenes
2012

The Atlantic salmon (Salmo Salar L.) notochord displays a dynamic transcriptome prior to and during vertebral segmentation

Shou Wang, Tomasz Furmanek, Harald Kryvi, Sindre Grotmol, Geir Kåre Totland, Christel Krossøy, Anna Wargelius
2012

Knockdown of salmon dead-end affect gonad morphology in 10 months old Atlantic salmon (Salmo Salar L.)

Anna Wargelius, Øyvind Drivenes, Trine Haugen, Per Gunnar Fjelldal, Eva Andersson, Hans-Øyvind Svensvik, Rolf Edvardsen, Geir Lasse Taranger
2011

Maternal 3'UTRs: from egg to onset of zygotic transcription in Atlantic cod

Lene Kleppe, Rolf Edvardsen, Heiner Kuhl, Ketil Malde, Tomasz Furmanek, Øyvind Drivenes, Richard Reinhardt, Geir Lasse Taranger, Anna Wargelius
2011

Control of sexual maturity in cod farming – status and future solution

Ørjan Karlsen, Trine Haugen, Øyvind Johan Korsøen, Ingegjerd Opstad, Håkon Magne Otterå, Ole Fredrik Skulstad, Anders Thorsen, Anna Wargelius, Geir Lasse Taranger
2010

Continuous light induces bone resorption and affects vertebral morphology in Atlantic salmon (Salmo salar L.) fed a phosphorous deficient diet

Robin Ørnsrud, Erik-Jan Lock, Tom Johnny Hansen, Rune Waagbø, Anna Wargelius, Laura Gil Martens, Adel El-Mowafi, Per Gunnar Fjelldal
2009

Dietary Fatty Acids and Inflammation in the vertebral column of Atlantic salmon (Salmo salar) smolts: A possible link to spinal deformities

Laura Gil Martens, Erik-Jan Lock, Per Gunnar Fjelldal, Anna Wargelius, Pedro Araujo, Bente Elisabeth Torstensen, Paul Eckhard Witten, Tom Johnny Hansen, Rune Waagbø, Robin Ørnsrud
2009

Deformations of the spinal column in Atlantic salmon

Per Gunnar Fjelldal, Robin Ørnsrud, Olav Breck, Anna Wargelius, Arne Berg, Kevin A. Glover, Ane Grini, Roar Sandvik, Rune Waagbø, Tom Johnny Hansen
2005

Elevated retinol levels do not cause spinal deformities in the developing salmon embryo

Robin Ørnsrud, Geir Kåre Totland, Anna Wargelius
1998

Detection of polymorphisms in the genes encoding Fas and Fas ligand in patients with primary Sjögren´s syndrome

Anne Isine Bolstad, Anna Wargelius, Roland Jonsson
1998

Detection of polymorphisms in the genes encoding Fas and Fas ligand in patients with primary Sjögren's syndrome

Anne Isine Bolstad, A. Wargelius, Roland Jonsson
1997

Screening for mutations in the <i>fas</i> gene in patientes with primary Sj@øgren's syndrome

Anne Isine Bolstad, A. Wargelius, Roland Jonsson

Annet tidsskriftbidrag

2016

Ulik laks i sør og nord

Erik Nordtorp Kjærner-Semb, Anna Wargelius, Rolf Edvardsen
Dagens næringsliv

Rapporter og avhandlinger

2017

Genetics behind puberty and adaptation in Atlantic Salmon revealed by genomic studies

Anna Wargelius, Rolf Edvardsen, Erik Nordtorp Kjærner-Semb, Kevin Glover
2015

Endrer gener for å få steril fisk

Anna Wargelius, Rolf Edvardsen
2001

A study of Six3-like genes involved in zebrafish eye and forebrain development

Wargelius, Anna Sofie

 

 
 
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